| Literature DB >> 26444492 |
Everton L F Ferreira1, David E Williams2, Laura P Ióca1, Raquel P Morais-Urano1, Mario F C Santos1, Brian O Patrick2, Luciana M Elias3, Simone P Lira3, Antonio G Ferreira4, Michel R Z Passarini5, Lara D Sette6, Raymond J Andersen2, Roberto G S Berlinck1.
Abstract
The structure of the fungal metabolite roussoellatide (1) has been established by spectroscopic and X-ray diffraction analyses. Results from feeding experiments with [1-(13)C]acetate, [2-(13)C]acetate, and [1,2-(13)C]acetate were consistent with a biosynthetic pathway to the unprecedented skeleton of 1 involving Favorskii rearrangements in separate pentaketides, subsequently joined via an intermolecular Diels-Alder reaction.Entities:
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Year: 2015 PMID： 26444492 DOI： 10.1021/acs.orglett.5b02060
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005