L de Boisanger1,2. 1. , 56 Kersland Street, Flat 1-2, Glasgow, G12 8BT, UK. louisdeboz@gmail.com. 2. University of Glasgow, University Avenue, Glasgow, G12 8QQ, UK. louisdeboz@gmail.com.
Abstract
BACKGROUND: This is a literature review of outcomes for patients with Guillain-Barré Syndrome (GBS) who require admission to the intensive care unit for mechanical ventilation. Respiratory distress is the leading cause of death in the acute phase, and occurs in about 25 % of patients. AIMS: The aim of this review is to compile, analyse, and summarise the most relevant literature looking at outcomes for Guillain-Barré (GB) patients requiring admission to the intensive care unit and mechanical ventilation. METHODS: A PubMed and Google-Scholar literature search was performed using the key words 'Guillain-Barré, Outcomes, Mechanical Ventilation, Prognosis, Mortality, ICU. All 7 papers from the years 2000-2014 which assessed outcomes for GBS patients requiring mechanical ventilation were included, and critically analysed. RESULTS: The parameters recorded by these studies looked at mortality, disability, length of hospitalisation, and complications. The mortality of GB patients requiring mechanical ventilation varied from 8.3 to 20 %, Disability was primarily measured by the GBS disability scale. One study deemed that a score of 0-1 was a positive outcome, and found that slightly over half 53.8 % of the patients fulfilled that criteria. Over half of the mechanically ventilated patients were required to be admitted for over 3 weeks. Complications during ICU admission are common, with bed-sores (40 %), pneumonia (30.2 %) and sepsis (17.4) being the most frequently encountered in one study. CONCLUSION: Accurate data are limited by the fact that these studies are retrospective, often covering long periods in the past. Larger, more recent, prospective, multi-centre studies will be required.
BACKGROUND: This is a literature review of outcomes for patients with Guillain-Barré Syndrome (GBS) who require admission to the intensive care unit for mechanical ventilation. Respiratory distress is the leading cause of death in the acute phase, and occurs in about 25 % of patients. AIMS: The aim of this review is to compile, analyse, and summarise the most relevant literature looking at outcomes for Guillain-Barré (GB) patients requiring admission to the intensive care unit and mechanical ventilation. METHODS: A PubMed and Google-Scholar literature search was performed using the key words 'Guillain-Barré, Outcomes, Mechanical Ventilation, Prognosis, Mortality, ICU. All 7 papers from the years 2000-2014 which assessed outcomes for GBSpatients requiring mechanical ventilation were included, and critically analysed. RESULTS: The parameters recorded by these studies looked at mortality, disability, length of hospitalisation, and complications. The mortality of GB patients requiring mechanical ventilation varied from 8.3 to 20 %, Disability was primarily measured by the GBS disability scale. One study deemed that a score of 0-1 was a positive outcome, and found that slightly over half 53.8 % of the patients fulfilled that criteria. Over half of the mechanically ventilated patients were required to be admitted for over 3 weeks. Complications during ICU admission are common, with bed-sores (40 %), pneumonia (30.2 %) and sepsis (17.4) being the most frequently encountered in one study. CONCLUSION: Accurate data are limited by the fact that these studies are retrospective, often covering long periods in the past. Larger, more recent, prospective, multi-centre studies will be required.
Authors: Stephan A Mayer; William M Coplin; Cherylee Chang; Jose Suarez; Daryl Gress; Michael N Diringer; Jeffery Frank; J Claude Hemphill; Gene Sung; Wade Smith; Edward M Manno; Andrew Kofke; Arthur Lam; Thorsten Steiner Journal: Neurocrit Care Date: 2006 Impact factor: 3.210
Authors: Archana B Netto; Arun B Taly; Girish Baburao Kulkarni; Umamaheswara G S Rao; Shivaji Rao Journal: Ann Indian Acad Neurol Date: 2011-10 Impact factor: 1.383
Authors: Ugarte Ubiergo Sebastián; Arenas Villamizar Angel Ricardo; Bruno C Alvarez; Angela Cubides; Angélica F Luna; Max Arroyo-Parejo; Cayri E Acuña; Agamenón V Quintero; Orlando Ch Villareal; Oscar S Pinillos; Elías Vieda; Manuel Bello; Susana Peña; Carmelo Dueñas-Castell; Gloria M V Rodriguez; Jorge L M Ranero; Rosa L M López; Sandra G Olaya; José C Vergara; Ana Tandazo; Juan P S Ospina; Igor M Leyton Soto; R A Fowler; John C Marshall Journal: J Crit Care Date: 2017-08-09 Impact factor: 3.425