Lorine Pelly1, Cathy Vardy1, Bridget Fernandez1, Leigh Anne Newhook1, Roger Chafe1. 1. Section of Pediatric Infectious Diseases (Pelly), Pediatrics and Child Health, University of Manitoba, Winnipeg, Man.; Discipline of Pediatrics (Vardy, Newhook, Chafe), Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL; Discipline of Genetics (Fernandez), Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL.
Abstract
BACKGROUND: Recent studies have reported increased prevalence for autism spectrum disorders in a number of geographical locations. Our objective was to determine the incidence and 1-year cohort prevalence for autism spectrum disorders in children less than 15 years of age and living in the Avalon Peninsula at the time of diagnosis. METHODS: Retrospective and prospective data were obtained from the Janeway Children's Health and Rehabilitation Centre (St. John's), including the identification and specific diagnosis for all children assessed for autism spectrum disorder from 2006 to 2010. Additional clinic data were reviewed to update the data until the end of 2013. RESULTS: From 2006 to 2010, 272 children had a diagnosis of autism spectrum disorder, averaging 54 new cases per year. The incidence of new cases increased from 10.1 to 16.7 cases per 10 000 per year from 2006 to 2010. At the end of 2013, the prevalence among children born in 2006 was 1 case of autism spectrum disorder per 46 children or 215.77 per 10 000. INTERPRETATION: We found higher rates of autism spectrum disorder than previously reported for this population. The prevalence in this region is also high when compared with other global populations. The high rate of diagnosis supports the need for a provincial autism spectrum disorder registry and further research on autism spectrum disorder within this population.
BACKGROUND: Recent studies have reported increased prevalence for autism spectrum disorders in a number of geographical locations. Our objective was to determine the incidence and 1-year cohort prevalence for autism spectrum disorders in children less than 15 years of age and living in the Avalon Peninsula at the time of diagnosis. METHODS: Retrospective and prospective data were obtained from the Janeway Children's Health and Rehabilitation Centre (St. John's), including the identification and specific diagnosis for all children assessed for autism spectrum disorder from 2006 to 2010. Additional clinic data were reviewed to update the data until the end of 2013. RESULTS: From 2006 to 2010, 272 children had a diagnosis of autism spectrum disorder, averaging 54 new cases per year. The incidence of new cases increased from 10.1 to 16.7 cases per 10 000 per year from 2006 to 2010. At the end of 2013, the prevalence among children born in 2006 was 1 case of autism spectrum disorder per 46 children or 215.77 per 10 000. INTERPRETATION: We found higher rates of autism spectrum disorder than previously reported for this population. The prevalence in this region is also high when compared with other global populations. The high rate of diagnosis supports the need for a provincial autism spectrum disorder registry and further research on autism spectrum disorder within this population.
Authors: H Ouellette-Kuntz; H Coo; C T Yu; M E Lewis; D Dewey; P E Hennessey; P D Jackman; M M Breitenbach; J J Holden Journal: Chronic Dis Inj Can Date: 2012-03
Authors: Krista Mahoney; David Buckley; Muhammed Alam; Sharon Penney; Terry-Lynn Young; Patrick Parfrey; Susan J Moore Journal: Epilepsy Res Date: 2011-09-29 Impact factor: 3.045
Authors: Gregory Ryan Handrigan; David Chitayat; Anath C Lionel; Maury Pinsk; Andrea K Vaags; Christian R Marshall; Sarah Dyack; Luis F Escobar; Bridget A Fernandez; Joseph C Stegman; Jill A Rosenfeld; Lisa G Shaffer; McKinsey Goodenberger; Jennelle C Hodge; Jason E Cain; Riyana Babul-Hirji; Dimitri J Stavropoulos; Verna Yiu; Stephen W Scherer; Norman D Rosenblum Journal: J Med Genet Date: 2013-01-18 Impact factor: 6.318
Authors: Hélène Ouellette-Kuntz; Helen Coo; Miu Lam; Marlene M Breitenbach; Paula E Hennessey; Paulette D Jackman; M E Suzanne Lewis; Deborah Dewey; François P Bernier; Amy M Chung Journal: J Autism Dev Disord Date: 2014-01
Authors: Eric Fombonne; Carlos Marcin; Ana Cecilia Manero; Ruth Bruno; Christian Diaz; Michele Villalobos; Katrina Ramsay; Benjamin Nealy Journal: J Autism Dev Disord Date: 2016-05
Authors: Lonnie Zwaigenbaum; Eric Duku; Eric Fombonne; Peter Szatmari; Isabel M Smith; Susan E Bryson; Pat Mirenda; Tracy Vaillancourt; Joanne Volden; Stelios Georgiades; Wendy Roberts; Teresa Bennett; Mayada Elsabbagh; Charlotte Waddell; Mandy Steiman; Rebecca Simon; Ruth Bruno Journal: Paediatr Child Health Date: 2018-07-02 Impact factor: 2.253
Authors: Elizabeth Lin; Robert Balogh; Caitlin McGarry; Avra Selick; Kristin Dobranowski; Andrew S Wilton; Yona Lunsky Journal: BMJ Open Date: 2016-09-02 Impact factor: 2.692