Literature DB >> 26441249

Therapy: Targeting chromatin remodelling proteins to treat pancreatic cancer.

Hugh Thomas.   

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Year:  2015        PMID: 26441249     DOI: 10.1038/nrgastro.2015.171

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN: 1759-5045            Impact factor:   46.802


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  1 in total

1.  Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.

Authors:  Pawel K Mazur; Alexander Herner; Stephano S Mello; Matthias Wirth; Simone Hausmann; Francisco J Sánchez-Rivera; Shane M Lofgren; Timo Kuschma; Stephan A Hahn; Deepak Vangala; Marija Trajkovic-Arsic; Aayush Gupta; Irina Heid; Peter B Noël; Rickmer Braren; Mert Erkan; Jörg Kleeff; Bence Sipos; Leanne C Sayles; Mathias Heikenwalder; Elisabeth Heßmann; Volker Ellenrieder; Irene Esposito; Tyler Jacks; James E Bradner; Purvesh Khatri; E Alejandro Sweet-Cordero; Laura D Attardi; Roland M Schmid; Guenter Schneider; Julien Sage; Jens T Siveke
Journal:  Nat Med       Date:  2015-09-21       Impact factor: 53.440

  1 in total
  3 in total

Review 1.  Trials and tribulations of pancreatic cancer immunotherapy.

Authors:  Daniel R Principe; Murray Korc; Suneel D Kamath; Hidayatullah G Munshi; Ajay Rana
Journal:  Cancer Lett       Date:  2021-02-04       Impact factor: 9.756

Review 2.  Precision Medicine for BRCA/PALB2-Mutated Pancreatic Cancer and Emerging Strategies to Improve Therapeutic Responses to PARP Inhibition.

Authors:  Daniel R Principe
Journal:  Cancers (Basel)       Date:  2022-02-11       Impact factor: 6.639

3.  XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer.

Authors:  Daniel R Principe; Rui Xiong; Yangfeng Li; Thao N D Pham; Suneel D Kamath; Oleksii Dubrovskyi; Kiira Ratia; Fei Huang; Jiong Zhao; Zhengnan Shen; Dinesh Thummuri; Zhou Daohong; Patrick W Underwood; Jose Trevino; Hidayatullah G Munshi; Gregory R J Thatcher; Ajay Rana
Journal:  Proc Natl Acad Sci U S A       Date:  2022-01-25       Impact factor: 12.779

  3 in total

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