Gregory J Goodman1, Arthur Swift, B Kent Remington. 1. Clayton and Carlton, Victoria, Australia; and Montreal, Quebec, and Calgary, Alberta, Canada From the Monash University; The Skin and Cancer Foundation; Westmount Institute of Plastic Surgery; Victoria Park MediSpa; St. Mary's Hospital, McGill University; and Remington Laser Dermatology Centre.
Abstract
BACKGROUND: Hyaluronic acids (HAs) are very popular temporary fillers with a very good safety record. Improvements and adaptations in clinical use are continuing. METHODS: We have assessed the available literature to investigate the relatively new Vycross technology that uses a mixture of high- and low-molecular-weight HAs with a relatively low but varying HA concentration with enhanced cross-linking to produce a number of products that have differing clinical indications. RESULTS: Voluma has the highest HA concentration at 20 mg/mL, a high G prime translating into lift capacity and cohesivity keeping the product capable to lift vertically adding structure, form, and volume, whereas Volbella has much lower concentration at 15 mg/mL, a lower G prime and cohesivity allowing it to be used in more a horizontal spreading fashion enabling a superficial approach to lips, lines, and more subtle depressions. Volift at 17.5 mg/mL HA is half way between the 2 other products, allowing more subtle lift capacity but retaining an element of spread making it a useful agent for the perioral region in general and in the treatment of fine lines. CONCLUSION: A range of products has been released that allows different components of facial structure, volume, and lines to be adequately addressed.
BACKGROUND:Hyaluronic acids (HAs) are very popular temporary fillers with a very good safety record. Improvements and adaptations in clinical use are continuing. METHODS: We have assessed the available literature to investigate the relatively new Vycross technology that uses a mixture of high- and low-molecular-weight HAs with a relatively low but varying HA concentration with enhanced cross-linking to produce a number of products that have differing clinical indications. RESULTS: Voluma has the highest HA concentration at 20 mg/mL, a high G prime translating into lift capacity and cohesivity keeping the product capable to lift vertically adding structure, form, and volume, whereas Volbella has much lower concentration at 15 mg/mL, a lower G prime and cohesivity allowing it to be used in more a horizontal spreading fashion enabling a superficial approach to lips, lines, and more subtle depressions. Volift at 17.5 mg/mL HA is half way between the 2 other products, allowing more subtle lift capacity but retaining an element of spread making it a useful agent for the perioral region in general and in the treatment of fine lines. CONCLUSION: A range of products has been released that allows different components of facial structure, volume, and lines to be adequately addressed.
Authors: Dario Bertossi; Riccardo Nocini; Berend van der Lei; Philippe Magistretti; Alessandro Gualdi; Ali Pirayesh; Alberto Marchetti Journal: Plast Reconstr Surg Glob Open Date: 2021-11-24