Literature DB >> 26439814

Lewis Basic Sulfide Catalyzed Electrophilic Bromocyclization of Cyclopropylmethyl Amide.

Ying-Chieh Wong1, Zhihai Ke2, Ying-Yeung Yeung2,1.   

Abstract

A Lewis basic sulfide catalyzed electrophilic bromocyclization of cyclopropylmethyl amide has been developed. The catalytic protocol is applicable to both 1,1- and 1,2-substituted cyclopropylmethyl amides, giving oxazolines and oxazines in good yields and excellent diastereoselectivity.

Entities:  

Year:  2015        PMID： 26439814     DOI： 10.1021/acs.orglett.5b02557

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress.

Authors:  Madia L Stama; Enza Lacivita; Liliya N Kirpotina; Mauro Niso; Roberto Perrone; Igor A Schepetkin; Mark T Quinn; Marcello Leopoldo
Journal:  ChemMedChem       Date:  2017-11-07       Impact factor: 3.466

2.  Boron tribromide as a reagent for anti-Markovnikov addition of HBr to cyclopropanes.

Authors:  Matthew H Gieuw; Shuming Chen; Zhihai Ke; K N Houk; Ying-Yeung Yeung
Journal:  Chem Sci       Date:  2020-08-04       Impact factor: 9.825
  2 in total

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