Literature DB >> 26439798

Secukinumab distributes into dermal interstitial fluid of psoriasis patients as demonstrated by open flow microperfusion.

Christian Dragatin1, Florine Polus2, Manfred Bodenlenz1, Claudio Calonder2, Birgit Aigner3, Katrin Irene Tiffner1, Julia Katharina Mader4, Maria Ratzer1, Ralph Woessner2, Thomas Rudolf Pieber1,4, Yi Cheng5, Christian Loesche2, Frank Sinner1,4, Gerard Bruin2.   

Abstract

Entities:  

Keywords:  dermal open flow microperfusion; monoclonal antibody; pharmacokinetics; psoriasis; secukinumab

Mesh：

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Year:  2015        PMID： 26439798     DOI： 10.1111/exd.12863

Source DB:  PubMed          Journal:  Exp Dermatol        ISSN： 0906-6705            Impact factor:   3.960


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  14 in total

1.  Guiding dose selection of monoclonal antibodies using a new parameter (AFTIR) for characterizing ligand binding systems.

Authors:  Sameed Ahmed; Miandra Ellis; Hongshan Li; Luca Pallucchini; Andrew M Stein
Journal:  J Pharmacokinet Pharmacodyn       Date:  2019-04-29       Impact factor: 2.745

Review 2.  Utility of Microdialysis in Infectious Disease Drug Development and Dose Optimization.

Authors:  Amelia N Deitchman; M Tobias Heinrichs; Vipada Khaowroongrueng; Satyawan B Jadhav; Hartmut Derendorf
Journal:  AAPS J       Date:  2016-12-09       Impact factor: 4.009

Review 3.  In Vivo Stability of Therapeutic Proteins.

Authors:  Joachim Schuster; Atanas Koulov; Hanns-Christian Mahler; Pascal Detampel; Joerg Huwyler; Satish Singh; Roman Mathaes
Journal:  Pharm Res       Date:  2020-01-03       Impact factor: 4.200

4.  LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation.

Authors:  Cornelia Pipper; Natalie Bordag; Bernadette Reiter; Kyriakos Economides; Peter Florian; Thomas Birngruber; Frank Sinner; Manfred Bodenlenz; Anita Eberl
Journal:  J Lipid Res       Date:  2019-01-29       Impact factor: 5.922

5.  Minimal Physiologically-Based Pharmacokinetic (mPBPK) Metamodeling of Target Engagement in Skin Informs Anti-IL17A Drug Development in Psoriasis.

Authors:  Vivaswath S Ayyar; Jong Bong Lee; Weirong Wang; Meghan Pryor; Yanli Zhuang; Thomas Wilde; An Vermeulen
Journal:  Front Pharmacol       Date:  2022-04-25       Impact factor: 5.988

6.  A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel disease model.

Authors:  Songmao Zheng; Jin Niu; Brian Geist; Damien Fink; Zhenhua Xu; Honghui Zhou; Weirong Wang
Journal:  MAbs       Date:  2020 Jan-Dec       Impact factor: 5.857

7.  Whole-Body Pharmacokinetics of Antibody in Mice Determined using Enzyme-Linked Immunosorbent Assay and Derivation of Tissue Interstitial Concentrations.

Authors:  Hsuan-Ping Chang; Se Jin Kim; Dhaval K Shah
Journal:  J Pharm Sci       Date:  2020-06-02       Impact factor: 3.534

8.  Assessing the Impact of Tissue Target Concentration Data on Uncertainty in In Vivo Target Coverage Predictions.

Authors:  A Tiwari; H Luo; X Chen; P Singh; I Bhattacharya; P Jasper; J E Tolsma; H M Jones; A Zutshi; A K Abraham
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2016-10-22

9.  Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence.

Authors:  Manfred Bodenlenz; Katrin I Tiffner; Reingard Raml; Thomas Augustin; Christian Dragatin; Thomas Birngruber; Denise Schimek; Gerd Schwagerle; Thomas R Pieber; Sam G Raney; Isadore Kanfer; Frank Sinner
Journal:  Clin Pharmacokinet       Date:  2017-01       Impact factor: 6.447

Review 10.  Pharmacokinetics and pharmacodynamics in the treatment of cutaneous leishmaniasis - challenges and opportunities.

Authors:  Katrien Van Bocxlaer; Simon L Croft
Journal:  RSC Med Chem       Date:  2021-01-07
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