Literature DB >> 26439248

Monocyte/HDL-cholesterol ratio predicts the definite stent thrombosis after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.

Elif Hande Ozcan Cetin1, Mehmet Serkan Cetin1, Uğur Canpolat1, Selahattin Aydin1, Serkan Topaloglu1, Dursun Aras1, Sinan Aydogdu1.   

Abstract

AIM: We investigated the predictive value of monocyte count to HDL ratio (M/H ratio) for stent thrombosis (ST) in ST elevation myocardial infarction (STEMI). PATIENTS &
METHODS: 1170 STEMI patients treated with primary PCI were followed-up for a median of 37.2 months.
RESULTS: During follow-up, 112 patients were diagnosed as 'definite' ST. The rate of ST was significantly highest in the third M/H ratio tertile. In Cox regression analysis, adjusted for other factors, having an M/H ratio in third tertile had a 2.2-fold increased risk of ST. Kaplan-Meier analysis revealed the higher occurrence of ST in the third tertile compared with others (p <0.001).
CONCLUSION: M/H ratio as a novel marker of inflammation seemed to be an independent predictor of ST in STEMI patients.

Entities:  

Keywords:  PCI; ST elevation myocardial infarction; inflammation; monocyte to HDL ratio; stent thrombosis

Mesh:

Substances:

Year:  2015        PMID: 26439248     DOI: 10.2217/bmm.15.74

Source DB:  PubMed          Journal:  Biomark Med        ISSN: 1752-0363            Impact factor:   2.851


  19 in total

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