| Literature DB >> 26438489 |
Anuradha Chowdhary1, Pradeep Kumar Singh2, Shallu Kathuria2, Ferry Hagen3, Jacques F Meis4.
Abstract
We compared EUCAST and CLSI antifungal susceptibility testing (AFST) methods for triazoles and amphotericin B against 124 clinical Mucorales isolates. The EUCAST method yielded MIC values 1- to 3-fold dilutions higher than those of the CLSI method for amphotericin B. The essential agreements between the two methods for triazoles were high, i.e., 99.1% (voriconazole), 98.3% (isavuconazole), and 87% (posaconazole), whereas it was significantly lower for amphotericin B (66.1%). Strategies for harmonization of the two methods for Mucorales AFST are warranted.Entities:
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Year: 2015 PMID: 26438489 PMCID: PMC4649204 DOI: 10.1128/AAC.02107-15
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191