| Literature DB >> 26436987 |
Khurrum Khan1, Amina I Malik, Sumayya J Almarzouqi, Michael L Morgan, Sushma Yalamanchili, Patricia Chevez-Barrios, Andrew G Lee.
Abstract
Central nervous system involvement from chronic lymphocytic leukemia (CLL) occurs infrequently, and manifestations include cognitive and cerebellar dysfunction and cranial nerve palsies. We report a 45-year-old man with CLL believed to be in clinical remission, who presented with vision loss and bilateral optic disc edema. His optic neuropathy due to CLL was proven by optic nerve sheath biopsy, and he experienced visual recovery after treatment with ibrutinib and intrathecal methotrexate.Entities:
Mesh：
Substances：
Year: 2016 PMID： 26436987 DOI： 10.1097/WNO.0000000000000300
Source DB: PubMed Journal: J Neuroophthalmol ISSN： 1070-8022 Impact factor: 3.042