| Literature DB >> 26436939 |
Pablo Young, María Massa, Bárbara C Finn, Gonzalo Fleire, Germán R Stemmelin, Amanda Ruades, Daniel Sutovsky, José G Casas, Pablo Dezanzo, Félix Vigovich, Julio E Bruetman.
Abstract
Intravascular lymphoma is a rare subtype of extranodal diffuse large B-cell lymphoma characterized by clonal proliferation of lymphocytes inside of small and medium caliber vessels. Its incidence is estimated at one case per million. The clinical picture is very variable, but frequently has skin and central nervous system involvement. It is diagnosed by demonstrating pathological blood vessel infiltration by lymphoma cells. We report a 44 years old male presenting with fever, malaise and erythematous lesions in the abdominal wall. An abdominal wall biopsy showed dilated vascular vessels with atypical cells in their lumen, compatible with large B-cell intravascular lymphoma. He was treated with rituximab, cyclophosphamide, adriamycin, vincristine and prednisone and an autologous hematopoietic stem cell transplantation, achieving a complete remission that has lasted two years.Entities:
Mesh:
Year: 2015 PMID: 26436939 DOI: 10.4067/S0034-98872015000800017
Source DB: PubMed Journal: Rev Med Chil ISSN: 0034-9887 Impact factor: 0.553