Literature DB >> 2643642

Agranulocytosis caused by dapsone therapy for granuloma annulare.

M N Potter1, P Yates, R Slade, C T Kennedy.   

Abstract

Dapsone has been suggested as a useful drug in the treatment of granuloma annulare; however, adverse reactions include a potentially life-threatening agranulocytosis. We report the case of a 50-year-old woman in whom agranulocytosis and septicemia developed after 7 weeks of therapy with dapsone for granuloma annulare. Full recovery followed cessation of this drug, but caution is advised in prescribing dapsone for relatively benign skin conditions.

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Year:  1989        PMID: 2643642     DOI: 10.1016/s0190-9622(89)70013-x

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  3 in total

1.  [Dapsone-induced agranulocytosis. The role of xenobiotic-metabolizing enzymes demonstrated by a case report].

Authors:  T K Hoffmann; S von Schmiedeberg; M Wulferink; R Thier; H Bier; T Ruzicka; P Lehmann
Journal:  Hautarzt       Date:  2005-07       Impact factor: 0.751

2.  Granuloma annulare treated with excimer laser.

Authors:  Roman Bronfenbrener; Jennifer Ragi; Sandy Milgraum
Journal:  J Clin Aesthet Dermatol       Date:  2012-11

3.  An unusual case of dapsone syndrome.

Authors:  Mary Grace
Journal:  Indian Dermatol Online J       Date:  2011-07
  3 in total

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