Literature DB >> 26436058

Anaesthetic Efficacy of Topical Benzocaine Gel Combined with Hyaluronidase for Supplemental Intrapulpal Injection in Teeth with Irreversible Pulpitis- A Double Blinded Clinical Trial.

Sujatha Gopal Sooraparaju1, M Abarajithan2, Emmanuel Solomon Sathish3, Nujella Bhaskara Padma Suryakumari4, Kranti Kiran Reddy Ealla5, Winner Gade6.   

Abstract

OBJECTIVE: Intrapulpal injection technique is one of the most commonly employed method to achieve profound pulpal anaesthesia during an endodontic procedure. To determine if the topical application of benzocaine gel along with hyaluronidase to the pulp chamber could reduce the pain felt with the intrapulpal injection technique.
MATERIALS AND METHODS: Two hundred patients with chronic irreversible pulpitis undergoing endodontic treatment for mandibular first molars in which the primary anaesthetic technique failed were selected and randomly divided into 2 groups. In the control group intrapulpal injection was administered with backpressure. In the experimental group topical application of 20% benzocaine gel mixed with hyaluronidase was done over the exposed pulp following which intrapulpal injection was administered with backpressure. Pain assessment was done on a visual analogue scale.
RESULTS: There was statistically significant difference (p<0.001) between the two groups. The mean value in the control group corresponded to the pain perception "strong", whereas that of the experimental group corresponded to the pain perception "weak".
CONCLUSION: Topical application of 20% benzocaine gel mixed with hyaluronidase to the exposed pulp reduces the pain encountered with the intrapulpal injection.

Entities:  

Keywords:  Hot pulp; IAN block; Pulpal anaesthesia

Year:  2015        PMID: 26436058      PMCID: PMC4576652          DOI: 10.7860/JCDR/2015/12575.6401

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  13 in total

1.  The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing.

Authors:  J Friskopp; M Nilsson; G Isacsson
Journal:  J Clin Periodontol       Date:  2001-05       Impact factor: 8.728

2.  Role of the anesthetic solution in intrapulpal anesthesia.

Authors:  J Birchfield; P A Rosenberg
Journal:  J Endod       Date:  1975-01       Impact factor: 4.171

3.  The use of hyaluronidase in regional nerve blocks.

Authors:  J E ECKENHOFF; C K KIRBY
Journal:  Anesthesiology       Date:  1951-01       Impact factor: 7.892

4.  Topical anesthetic as an adjunct to local anesthesia during pulpectomies.

Authors:  M DeNunzio
Journal:  J Endod       Date:  1998-03       Impact factor: 4.171

5.  Hyaluronidase and peribulbar block.

Authors:  G A Dempsey; P J Barrett; I J Kirby
Journal:  Br J Anaesth       Date:  1997-06       Impact factor: 9.166

6.  Intrapulpal injection: factors related to effectiveness.

Authors:  J VanGheluwe; R Walton
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  1997-01

7.  Evaluation of the Akinosi mandibular block technique in oral surgery.

Authors:  A L Sisk
Journal:  J Oral Maxillofac Surg       Date:  1986-02       Impact factor: 1.895

8.  Is hyaluronidase helpful for peribulbar anaesthesia?

Authors:  R J Bowman; D K Newman; E C Richardson; A B Callear; D W Flanagan
Journal:  Eye (Lond)       Date:  1997       Impact factor: 3.775

9.  Comparative evaluation of the efficacy of 2% lidocaine containing 1:200,000 epinephrine with and without hyaluronidase (75 IU) in patients with irreversible pulpitis.

Authors:  Sarvepalli Venkata Satish; Krishna Prasad Shetty; Krishnarao Kilaru; Puridi Bhargavi; E Srinivas Reddy; Aditya Bellutgi
Journal:  J Endod       Date:  2013-06-19       Impact factor: 4.171

10.  Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitis.

Authors:  Elizabeth Claffey; Al Reader; John Nusstein; Mike Beck; Joel Weaver
Journal:  J Endod       Date:  2004-08       Impact factor: 4.171

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  5 in total

1.  Caries Color, Extent, and Preoperative Pain as Predictors of Pulp Status in Primary Teeth.

Authors:  Faezeh Ghaderi; Zahra Jowkar; Alireza Tadayon
Journal:  Clin Cosmet Investig Dent       Date:  2020-07-03

2.  Clinical Considerations of Intrapulpal Anesthesia in Pediatric Dentistry.

Authors:  Saravana Karthikeyan Balasubramanian; Velmurugan Natanasabapathy; Divya Vinayachandran
Journal:  Anesth Essays Res       Date:  2017 Jan-Mar

3.  Influence of Lignocaine Hydrochloride with Adrenaline on Free Active Chlorine Content of Sodium Hypochlorite Solution Admixed in Various Proportions.

Authors:  Ishwarya Gurucharan; Charanya Chandrasekaran; Balasubramanian Saravanakarthikeyan; Sekar Mahalaxmi
Journal:  Eur Endod J       Date:  2021-01-26

4.  Needle Gauge Influences Pain Perception During Intrapulpal Anaesthesia - A Randomized Clinical Trial.

Authors:  Nandini Suresh; Vishnupriya Koteeswaran; Velmurugan Natanasabapathy; Kinnari Kasabwala; Dinesh Kowsky
Journal:  Eur Endod J       Date:  2020-12

5.  Comparison of the Anaesthesia Success Rate in Maxillary First and Second Molars with 3% Prilocaine as the Anaesthetic Agent.

Authors:  Masoud Parirokh; Iman Samadi; Nouzar Nakhaee; Paul Abbott
Journal:  Eur Endod J       Date:  2021-12
  5 in total

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