Literature DB >> 26435142

Modulation of ROS production in photodynamic therapy using a pH controlled photoinduced electron transfer (PET) based sensitiser.

Jordan Atchison1, Sukanta Kamila1, Conor McEwan1, Heather Nesbitt1, James Davis2, Colin Fowley1, Bridgeen Callan1, Anthony P McHale1, John F Callan1.   

Abstract

A new sensitiser (4) for use in photodynamic therapy (PDT) has been developed to enable control of ROS production as a function of pH. This pH dependent PDT behaviour was tested in HeLa cells and in SCID mice bearing human xenograft pancreatic cancer (BxPC-3) tumours.

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Year:  2015        PMID： 26435142     DOI： 10.1039/c5cc07022h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Magnetic and pH dual-responsive mesoporous silica nanocomposites for effective and low-toxic photodynamic therapy.

Authors:  Jieqiong Zhan; Zhiqiang Ma; Dan Wang; Xinfang Li; Xiangui Li; Lijing Le; Anfeng Kang; Pengwei Hu; Lan She; Feng Yang
Journal:  Int J Nanomedicine       Date:  2017-04-10

2.  A light-induced nitric oxide controllable release nano-platform based on diketopyrrolopyrrole derivatives for pH-responsive photodynamic/photothermal synergistic cancer therapy.

Authors:  Ya Wang; Xiaoyu Huang; Yunyun Tang; Jianhua Zou; Peng Wang; Yewei Zhang; Weili Si; Wei Huang; Xiaochen Dong
Journal:  Chem Sci       Date:  2018-08-29       Impact factor: 9.825

3.  A series of photosensitizers with incremental positive electric charges for photodynamic antitumor therapy.

Authors:  Shufeng Yan; Qingqing Huang; Xiaorong Song; Zhuo Chen; Mingdong Huang; Juncheng Zhang
Journal:  RSC Adv       Date:  2019-08-08       Impact factor: 3.361
  3 in total

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