| Literature DB >> 26435066 |
Huabin Liang1, Min Lee1, Xia Jin1.
Abstract
Flaviviruses comprise approximately 70 closely related RNA viruses. These include several mosquito-borne pathogens, such as yellow fever virus (YFV), dengue virus (DENV), and Japanese encephalitis virus (JEV), which can cause significant human diseases and thus are of great medical importance. Vaccines against both YFV and JEV have been used successfully in humans for decades; however, the development of a DENV vaccine has encountered considerable obstacles. Here, we review the protective immune responses elicited by the vaccine against YFV to provide some insights into the development of a protective DENV vaccine.Entities:
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Year: 2015 PMID: 26435066 PMCID: PMC4711684 DOI: 10.1038/cmi.2015.76
Source DB: PubMed Journal: Cell Mol Immunol ISSN: 1672-7681 Impact factor: 11.530