| Literature DB >> 26428541 |
Yazan Migdady1, Mohammed Salhab2,3, Nam H Dang1, Merry J Markham1, Adam J Olszewski3,4.
Abstract
We evaluated the association of baseline prognostic factors with conditional net survival among survivors of six subtypes non-Hodgkin lymphoma using the SEER program data from 2000-2012. Among 2-year survivors, further prognosis markedly improved in Burkitt's (BL) and diffuse large B-cell lymphoma (DLBCL), and became the same as for follicular lymphoma (5-year net survival ≥ 85%). Mantle cell lymphoma (MCL) demonstrated the worst prognosis of all studied histologies up to 5 years of survivorship. Age and stage lost prognostic significance in BL within 2 years from diagnosis. Racial disparities in net survival disappeared within 2 years for all subtypes, except in chronic lymphocytic leukemia, where black patients had persistently worse prognosis, and in MCL, where they had unexpectedly better prognosis than other races after 2 years. Many baseline factors may lose their initial prognostic value for lymphoma survivors, which should be considered when counseling patients about their prognosis and long-term surveillance.Entities:
Keywords: Burkitt lymphoma; conditional survival; diffuse large B-cell lymphoma; epidemiology; non-Hodgkin lymphoma; relative survival
Mesh:
Year: 2015 PMID: 26428541 DOI: 10.3109/10428194.2015.1102246
Source DB: PubMed Journal: Leuk Lymphoma ISSN: 1026-8022