Hosein Sharifi1, Mohammad Bagher Minaie2, Mohammad Javad Qasemzadeh3, Nematollah Ataei4, Mohammad Gharehbeglou3, Mojtaba Heydari5. 1. Persian Medicine & Pharmacy Research Center, School of traditional Medicine, Tehran University of Medical Science, Tehran, Iran. 2. Persian Medicine & Pharmacy Research Center, School of traditional Medicine, Tehran University of Medical Science, Tehran, Iran bagherminaei@yahoo.com. 3. Department of Medicine, Qom Branch, Islamic Azad University, Qom, Iran. 4. Department of Pediatric Nephrology, Children's Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran. 5. Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Abstract
AIM: To evaluate the efficacy of topical use of Matricaria recutita L oil in the treatment of enuresis in children. METHODS:Eighty patients diagnosed as monosymptomatic nocturnal or daytime enuresis were allocated to receive Matricaria recutita L (chamomile) oil or placebo topically for 6 weeks in a double-blind randomized placebo-controlled trial with a parallel design. Patients were evaluated prior to and following 8 weeks of the intervention in terms of frequency of enuresis and any observed adverse events. RESULTS: The mean frequency of enuresis at the first, second, and third 2 weeks was lower in the intervention group compared with the placebo group, and the differences were statistically significant (P < .001, P = .03, and P < .001, respectively). There was no report of any adverse event in the study groups. CONCLUSION: The findings of this study showed that the topical use of (chamomile) oil can decrease the frequency of nocturia in children with monosymptomatic nocturnal or daytime enuresis.
RCT Entities:
AIM: To evaluate the efficacy of topical use of Matricaria recutita L oil in the treatment of enuresis in children. METHODS: Eighty patients diagnosed as monosymptomatic nocturnal or daytime enuresis were allocated to receive Matricaria recutita L (chamomile) oil or placebo topically for 6 weeks in a double-blind randomized placebo-controlled trial with a parallel design. Patients were evaluated prior to and following 8 weeks of the intervention in terms of frequency of enuresis and any observed adverse events. RESULTS: The mean frequency of enuresis at the first, second, and third 2 weeks was lower in the intervention group compared with the placebo group, and the differences were statistically significant (P < .001, P = .03, and P < .001, respectively). There was no report of any adverse event in the study groups. CONCLUSION: The findings of this study showed that the topical use of (chamomile) oil can decrease the frequency of nocturia in children with monosymptomatic nocturnal or daytime enuresis.
Authors: Morteza Jarrahi; Abbas Ali Vafaei; Abbas Ali Taherian; Hossein Miladi; Ali Rashidi Pour Journal: Nat Prod Res Date: 2010-05 Impact factor: 2.861