| Literature DB >> 26426936 |
Kenneth K C Hong1, Graham E Ball1, David StC Black1, Naresh Kumar1.
Abstract
The first total synthesis of rottlerin is described. The methodology allows the development of potential novel protein kinase C δ (PKCδ) analogues for better treatment of various diseases. Kamalachalcone A and dimeric rottlerin were synthesized in a very practical and economical way using FeCl3 as a catalyst.Entities:
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Year: 2015 PMID： 26426936 DOI： 10.1021/acs.joc.5b01827
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354