Literature DB >> 26426114

Ultratrace DNA Detection Based on the Condensing-Enrichment Effect of Superwettable Microchips.

Li-Ping Xu1, Yanxia Chen1, Gao Yang2, Wanxin Shi1, Bing Dai1, Guannan Li2, Yanhua Cao1, Yongqiang Wen1, Xueji Zhang1, Shutao Wang2.   

Abstract

A sensitive nucleic acid detection platform based on superhydrophilic microwells spotted on a superhydrophobic substrate is fabricated. Due to the wettability differences, ultratrace DNA molecules are enriched and the fluorescent signals are amplified to allow more sensitive detection. The biosensing interface based on superwettable materials provides a simple and cost-effective way for ultratrace DNA sensing.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  DNA detection; condensing enrichment; microchips; superhydrophilic; superhydrophobic; ultratrace analysis

Mesh:

Substances:

Year:  2015        PMID: 26426114     DOI: 10.1002/adma.201502982

Source DB:  PubMed          Journal:  Adv Mater        ISSN: 0935-9648            Impact factor:   30.849


  11 in total

1.  Manipulating the hydrophobicity of DNA as a universal strategy for visual biosensing.

Authors:  Zhong Feng Gao; Rui Liu; Jinhua Wang; Jun Dai; Wei-Hua Huang; Mingjie Liu; Shutao Wang; Fan Xia; Shusheng Zhang; Lei Jiang
Journal:  Nat Protoc       Date:  2020-01-08       Impact factor: 13.491

2.  Selective and sensitive detection of MiRNA-21 based on gold-nanorod functionalized polydiacetylene microtube waveguide.

Authors:  Yu Zhu; Dong Qiu; Guang Yang; Mengqiao Wang; Qijin Zhang; Pei Wang; Hai Ming; Douguo Zhang; Yue Yu; Gang Zou; Ramachandram Badugu; Joseph R Lakowicz
Journal:  Biosens Bioelectron       Date:  2016-05-06       Impact factor: 10.618

3.  Dendritic porous silica nanoparticles with high-curvature structures for a dual-mode DNA sensor based on fluorometer and person glucose meter.

Authors:  Yulu Wang; Yuemeng Yang; Tingting Wu; Xueji Zhang; Rongming Wang; Xin Du; Li-Ping Xu
Journal:  Mikrochim Acta       Date:  2021-11-04       Impact factor: 5.833

Review 4.  Tailoring Materials with Specific Wettability in Biomedical Engineering.

Authors:  Lingyu Sun; Jiahui Guo; Hanxu Chen; Dagan Zhang; Luoran Shang; Bing Zhang; Yuanjin Zhao
Journal:  Adv Sci (Weinh)       Date:  2021-08-08       Impact factor: 16.806

5.  Evaporation-Induced Biomolecule Detection on Versatile Superhydrophilic Patterned Surfaces: Glucose and DNA Assay.

Authors:  Pinar Beyazkilic; Abtin Saateh; Mehmet Bayindir; Caglar Elbuken
Journal:  ACS Omega       Date:  2018-10-18

6.  A Nanostructured Microfluidic Immunoassay Platform for Highly Sensitive Infectious Pathogen Detection.

Authors:  Xu Yu; Yiqiu Xia; Yi Tang; Wen-Long Zhang; Yin-Ting Yeh; Huaguang Lu; Si-Yang Zheng
Journal:  Small       Date:  2017-06       Impact factor: 13.281

7.  Wetting ridge assisted programmed magnetic actuation of droplets on ferrofluid-infused surface.

Authors:  Jianqiang Zhang; Xuejiao Wang; Zhaoyue Wang; Shangfa Pan; Bo Yi; Liqing Ai; Jun Gao; Frieder Mugele; Xi Yao
Journal:  Nat Commun       Date:  2021-12-08       Impact factor: 14.919

Review 8.  Superwettable Biosensor for Disease Biomarker Detection.

Authors:  Yun Jun Yang; Zhong Feng Gao
Journal:  Front Bioeng Biotechnol       Date:  2022-03-28

Review 9.  Micro/Nanopatterned Superhydrophobic Surfaces Fabrication for Biomolecules and Biomaterials Manipulation and Analysis.

Authors:  Marco Allione; Tania Limongi; Monica Marini; Bruno Torre; Peng Zhang; Manola Moretti; Gerardo Perozziello; Patrizio Candeloro; Lucia Napione; Candido Fabrizio Pirri; Enzo Di Fabrizio
Journal:  Micromachines (Basel)       Date:  2021-11-30       Impact factor: 2.891

Review 10.  Recent Developments in Artificial Super-Wettable Surfaces Based on Bioinspired Polymeric Materials for Biomedical Applications.

Authors:  Ansar Abbas; Chen Zhang; Muhammad Asad; Ahsan Waqas; Asma Khatoon; Sameer Hussain; Sajjad Husain Mir
Journal:  Polymers (Basel)       Date:  2022-01-07       Impact factor: 4.329

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