| Literature DB >> 26426114 |
Li-Ping Xu1, Yanxia Chen1, Gao Yang2, Wanxin Shi1, Bing Dai1, Guannan Li2, Yanhua Cao1, Yongqiang Wen1, Xueji Zhang1, Shutao Wang2.
Abstract
A sensitive nucleic acid detection platform based on superhydrophilic microwells spotted on a superhydrophobic substrate is fabricated. Due to the wettability differences, ultratrace DNA molecules are enriched and the fluorescent signals are amplified to allow more sensitive detection. The biosensing interface based on superwettable materials provides a simple and cost-effective way for ultratrace DNA sensing.Keywords: DNA detection; condensing enrichment; microchips; superhydrophilic; superhydrophobic; ultratrace analysis
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Year: 2015 PMID: 26426114 DOI: 10.1002/adma.201502982
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849