| Literature DB >> 2642554 |
Abstract
Six model amine peroxides (4-9) were synthesized as targeted antimalarial oxidants. They were approximately 1 order of magnitude more potent than tert-butyl hydroperoxide (3) in vitro against Plasmodium falciparum, but like 3, they were inactive in vivo against Plasmodium berghei.Entities:
Mesh：
Substances：
Year: 1989 PMID： 2642554 DOI： 10.1021/jm00121a013
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446