Literature DB >> 2642553

Rational design of enzyme inhibitors: multisubstrate analogue inhibitors.

A D Broom1.   

Abstract

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Year:  1989        PMID： 2642553     DOI： 10.1021/jm00121a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

1.  Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties.

Authors:  Genbin Shi; Gary Shaw; Yu-He Liang; Priadarsini Subburaman; Yue Li; Yan Wu; Honggao Yan; Xinhua Ji
Journal:  Bioorg Med Chem       Date:  2011-11-23       Impact factor: 3.641

2.  Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: structure-activity relationships of the nucleobase domain of 5'-O-[N-(salicyl)sulfamoyl]adenosine.

Authors:  João Neres; Nicholas P Labello; Ravindranadh V Somu; Helena I Boshoff; Daniel J Wilson; Jagadeshwar Vannada; Liqiang Chen; Clifton E Barry; Eric M Bennett; Courtney C Aldrich
Journal:  J Med Chem       Date:  2008-08-09       Impact factor: 7.446

3.  Kinetic and inhibition studies of dihydroxybenzoate-AMP ligase from Escherichia coli.

Authors:  Alison L Sikora; Daniel J Wilson; Courtney C Aldrich; John S Blanchard
Journal:  Biochemistry       Date:  2010-05-04       Impact factor: 3.162

4.  Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124.

Authors:  Douglas S Auld; Scott Lovell; Natasha Thorne; Wendy A Lea; David J Maloney; Min Shen; Ganesha Rai; Kevin P Battaile; Craig J Thomas; Anton Simeonov; Robert P Hanzlik; James Inglese
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-01       Impact factor: 11.205

5.  Rational drug-design approach supported with thermodynamic studies - a peptide leader for the efficient bi-substrate inhibitor of protein kinase CK2.

Authors:  Maria Winiewska-Szajewska; Dawid Płonka; Igor Zhukov; Jarosław Poznański
Journal:  Sci Rep       Date:  2019-07-29       Impact factor: 4.379

6.  ATP-dependent ligases in trypanothione biosynthesis--kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.

Authors:  Sandra L Oza; Shoujun Chen; Susan Wyllie; James K Coward; Alan H Fairlamb
Journal:  FEBS J       Date:  2008-11       Impact factor: 5.542
  6 in total

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