Literature DB >> 26425172

Spinal neural fibrolipoma: A case report and review of the literature.

Cigdem Tokyol1, Adem Aslan2, Güler Senyildiz Hastürk3, Emre Kacar4, Mehmet Gazi Boyaci2.   

Abstract

Neural fibrolipoma is characterized by infiltration of the epineurium by adipose and fibrous tissue. Intradural spinal cases are extremely rare. We report an unusual case of spinal neural fibrolipoma. A 31-year-old pregnant woman presented due to weakness of right leg (muscle strength 2/5). Magnetic resonance (MR) evaluation of the spine revealed an extramedullary intradural mass at the T1-T4 level. MR findings were suggesting a dermoid cyst or a lipoma. Subtotal surgical excision of the tumor was done. Histopathological examination showed enlarged nerve bundles infiltrated by fibroadipose tissue. Thus, the diagnosis of neural fibrolipoma was established. One month after surgery, lumbar MR showed residual tumor tissue, but successful decompression of the spinal cord. Six months after surgery, the neurological examination, muscle strength 4/5 evaluated. Neural fibrolipoma is characterized by infiltration of the epineurium by adipose and fibrous tissue. The tissue grows between and around nerve bundles thereby causing enlargement of the affected nerve. Neural fibrolipoma is a benign lesion with no effective therapy. Surgical excision usually causes severe damage of the involved nerve. Although spinal cases are extremely rare, it should be included in the differential diagnosis of extramedullary intradural masses.

Entities:  

Keywords:  Hamartoma; pathology; spine

Year:  2015        PMID: 26425172      PMCID: PMC4558819          DOI: 10.4103/1793-5482.162727

Source DB:  PubMed          Journal:  Asian J Neurosurg


  11 in total

1.  Intraneural lipoma of the ulnar nerve.

Authors:  Laura A Bonneau; Stephen J Delatte; Michael L Bentz
Journal:  Plast Reconstr Surg       Date:  2009-01       Impact factor: 4.730

2.  Carpal tunnel syndrome due to fibrolipomatous hamartoma of the median nerve.

Authors:  Jamal Louaste; Hassan Zejjari; Mohamed Chkoura; Aziz Houmadi; Khalid Rachid
Journal:  Hand (N Y)       Date:  2010-08-24

3.  Fibrolipomatous hamartoma of nerve arising in the brachial plexus.

Authors:  A J Price; J P Compson; E Calonje
Journal:  J Hand Surg Br       Date:  1995-02

4.  Fibrolipomatous hamartoma of a cranial nerve.

Authors:  E Berti; F Roncaroli
Journal:  Histopathology       Date:  1994-04       Impact factor: 5.087

5.  Lipofibromatous hamartoma of nerve.

Authors:  P C Amadio; H M Reiman; J H Dobyns
Journal:  J Hand Surg Am       Date:  1988-01       Impact factor: 2.230

6.  Intraneural lipoma of the radial nerve presenting as Wartenberg syndrome: A case report and review of literature.

Authors:  Chenicheri Balakrishnan; Rebecca C Bachusz; Anila Balakrishnan; David Elliot; Daniel Careaga
Journal:  Can J Plast Surg       Date:  2009

7.  From the archives of the AFIP. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation.

Authors:  M D Murphey; W S Smith; S E Smith; M J Kransdorf; H T Temple
Journal:  Radiographics       Date:  1999 Sep-Oct       Impact factor: 5.333

Review 8.  Neural fibrolipoma of the foot: a case report.

Authors:  B G Donley; M Neel; H M Mitias
Journal:  Foot Ankle Int       Date:  1996-11       Impact factor: 2.827

9.  Fibrolipomatous hamartoma of nerve. A clinicopathologic analysis of 26 cases.

Authors:  T A Silverman; F M Enzinger
Journal:  Am J Surg Pathol       Date:  1985-01       Impact factor: 6.394

Review 10.  Fibrolipomatous hamartoma of nerve.

Authors:  C Bibbo; A M Warren
Journal:  J Foot Ankle Surg       Date:  1994 Jan-Feb       Impact factor: 1.286

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  1 in total

1.  Fibrolipomatous Hamartoma of Median Nerve - A Diagnostic Challenge.

Authors:  Vikrant Rai; G S Sabhikhi; Pankaj Sircar; Dev Kumar; Rohit Kundra; Madhan Jeyaraman
Journal:  J Orthop Case Rep       Date:  2021-11
  1 in total

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