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Literature DB >> 2642371

Why clinical trials of AIDS vaccines are premature.

W K Mariner¹.

Abstract

Entities: Disease

Keywords: Biomedical and Behavioral Research; Health Care and Public Health

Mesh：

Substances：
Viral Vaccines

Year: 1989 PMID： 2642371 PMCID： PMC1349480 DOI： 10.2105/ajph.79.1.86

Source DB: PubMed Journal: Am J Public Health ISSN： 0090-0036 Impact factor: 9.308

× No keyword cloud information.

23 in total

1. Long-term cultures of HTLV-III--infected T cells: a model of cytopathology of T-cell depletion in AIDS.

Authors: D Zagury; J Bernard; R Leonard; R Cheynier; M Feldman; P S Sarin; R C Gallo
Journal: Science Date: 1986-02-21 Impact factor: 47.728

Review 2. HTLV-III/LAV and the origin and pathogenesis of AIDS.

Authors: R C Gallo; M Robert-Guroff; F Wong-Staal; M S Reitz; S K Arya; H Z Streicher
Journal: Int Arch Allergy Appl Immunol Date: 1987

3. Getting to market: the scientific and legal climate for developing an AIDS vaccine.

Authors: W K Mariner; R C Gallo
Journal: Law Med Health Care Date: 1987

4. Ethical and social issues in the development of new drugs and vaccines.

Authors: D J Rothman
Journal: Bull N Y Acad Med Date: 1987 Jul-Aug

5. Obstacles to an AIDS vaccine.

Authors: D M Barnes
Journal: Science Date: 1988-05-06 Impact factor: 47.728

6. Long-term seropositivity for human T-lymphotropic virus type III in homosexual men without the acquired immunodeficiency syndrome: development of immunologic and clinical abnormalities. A longitudinal study.

Authors: M Melbye; R J Biggar; P Ebbesen; C Neuland; J J Goedert; V Faber; I Lorenzen; P Skinhøj; R C Gallo; W A Blattner
Journal: Ann Intern Med Date: 1986-04 Impact factor: 25.391

7. Persistent infection of chimpanzees with human T-lymphotropic virus type III/lymphadenopathy-associated virus: a potential model for acquired immunodeficiency syndrome.

Authors: P N Fultz; H M McClure; R B Swenson; C R McGrath; A Brodie; J P Getchell; F C Jensen; D C Anderson; J R Broderson; D P Francis
Journal: J Virol Date: 1986-04 Impact factor: 5.103

Why clinical trials of AIDS vaccines are premature.

1. Long-term cultures of HTLV-III--infected T cells: a model of cytopathology of T-cell depletion in AIDS.

Review 2. HTLV-III/LAV and the origin and pathogenesis of AIDS.

3. Getting to market: the scientific and legal climate for developing an AIDS vaccine.

4. Ethical and social issues in the development of new drugs and vaccines.

5. Obstacles to an AIDS vaccine.

6. Long-term seropositivity for human T-lymphotropic virus type III in homosexual men without the acquired immunodeficiency syndrome: development of immunologic and clinical abnormalities. A longitudinal study.

7. Persistent infection of chimpanzees with human T-lymphotropic virus type III/lymphadenopathy-associated virus: a potential model for acquired immunodeficiency syndrome.

8. Genetic variation in HTLV-III/LAV over time in patients with AIDS or at risk for AIDS.

9. The development of an AIDS vaccine: progress and promise.

10. T-cell responses to human immunodeficiency virus (HIV) and its recombinant antigens in HIV-infected chimpanzees.

Review 1. Ethical problems raised by anti-HIV vaccination.

2. New FDA drug approval policies and HIV vaccine development.

3. The ethical approach to AIDS: a bibliographical review.

4. HIV vaccine trials: will intravenous drug users enroll?