| Literature DB >> 26422625 |
Tilman B Drüeke1, Ziad A Massy1,2.
Abstract
Iron deficiency in patients with chronic kidney disease (CKD) can be corrected by the oral or intravenous route. The natural intestinal barrier against iron overload is circumvented by intravenous iron. The balance between benefit and risk of high iron doses remains unclear. In a randomized controlled trial in CKD patients, Agarwal et al. find similar effects of oral and intravenous iron on hemoglobin levels and kidney function decline but more serious cardiovascular events and infections with intravenous iron.Entities:
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Year: 2015 PMID: 26422625 DOI: 10.1038/ki.2015.189
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612