| Literature DB >> 26422558 |
Jana Filipova1, Lucie Rihova2, Pavla Vsianska2, Zuzana Kufova3, Elena Kryukova3, Fedor Kryukov3, Roman Hajek4.
Abstract
Flow cytometry (FCM) has found its application in clinical diagnosis and evaluation of monoclonal gammopathies (MG). Although, research has been mainly focused on multiple myeloma (MM), nowadays FCM becomes to be potential tool in the field of AL amyloidosis. Clonal plasma cells identification and specific phenotype profile detection is important for diagnosis, monitoring and prognosis of AL amyloidosis. Therefore, FCM could be a perspective method for study not only MM but also AL amyloidosis. This review provides an overview and possibilities of FCM application in AL amyloidosis.Entities:
Keywords: AL amyloidosis; Flow cytometry; Monoclonal gammopathy; Plasma cell
Year: 2015 PMID: 26422558 DOI: 10.1016/j.leukres.2015.07.002
Source DB: PubMed Journal: Leuk Res ISSN: 0145-2126 Impact factor: 3.156