| Literature DB >> 26418013 |
Misa Gokyu, Hiroaki Kobayashi, Hiromi Nanbara, Takeaki Sudo, Yuichi Ikeda, Tomonari Suda, Yuichi Izumi.
Abstract
Entities:
Year: 2015 PMID: 26418013 PMCID: PMC4587885 DOI: 10.1371/journal.pone.0139759
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 2Upregulation of TSP-1 in THP-1 cells by P. gingivalis LPS stimulation.
(A) THP-1 cells were stimulated by P. gingivalis LPS at concentrations of 0, 0.0001, 0.001, 0.01, 0.1, or 1.0 μg/ml for 4 h. P. gingivalis LPS increased TSP-1 mRNA expression in a dose-dependent manner in THP-1 cells. (B) THP-1 cells were stimulated by 1.0 µg/ml of P. gingivalis LPS for 0, 1, 2, 4, 12, 24, 48, or 72 h. P. gingivalis LPS increased TSP-1 mRNA expression in a time-dependent manner in THP-1 cells. (C) THP-1 cells were stimulated with P. gingivalis LPS at concentrations of 0, 0.01, 0.1, or 1.0 μg/ml for 72 h. P. gingivalis LPS increased TSP-1 protein production in a dose-dependent manner in THP-1 cells. (D) THP-1 cells were stimulated with 1.0 μg/ml of P. gingivalis LPS for 0, 1, 4, 6, 12, 24, 48, or 72 h. P. gingivalis LPS increased TSP-1 protein production in a time-dependent manner in THP-1 cells. (E) PMA-treated THP-1 cells were stimulated with P. gingivalis LPS at concentrations of 0, 0.01, 0.1, or 1.0 μg/ml for 4 h. P. gingivalis LPS increased TSP-1 protein production in a dose-dependent manner in PMA-treated THP-1 cells.