Yongcheng Ren1,2, Xinping Luo2, Chongjian Wang1, Lei Yin3, Chao Pang3, Tianping Feng3, Bingyuan Wang1,2, Lu Zhang1,2, Linlin Li1, Xiangyu Yang1,2, Hongyan Zhang1,2, Jingzhi Zhao3, Dongsheng Hu1,2. 1. Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou , 450001, People's Republic of China. 2. Department of Prevention Medicine, Shenzhen University School of Medicine, Shenzhen , 518060, People's Republic of China. 3. Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou , 450003, People's Republic of China.
Abstract
INTRODUCTION: A meta-analysis of studies assessing the prevalence of hypertriglyceridemic waist and an association with risk of type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: PubMed, EMBASE, Web of Science, CNKI, CQVIP and Wanfang databases were searched for studies of the prevalence of hypertriglyceridemic waist or association with risk of T2DM. Reference lists of each original article were also searched. A random-effects model was used to synthesize the combined prevalence and odds ratios. Publication bias and substantial heterogeneity were examined. RESULTS: Twenty-five eligible studies involving 93 194 participants (93 194 for prevalence and 34 199 for odds ratios): 17 articles of prevalence, and 8 of both prevalence and risk of T2DM. Prevalence of hypertriglyceridemic waist ranged from 4% to 47%, with pooled prevalence of 18% (95% CI 13-23%), overall: 18% (95% CI 13-23%) for men and 19% (95% CI 13-24%) for women. Odds ratios ranged from 2.8 to 9.6 for T2MD in overall, with pooled odds ratios of 4.18 (95% CI 3.55-4.92), overall: 3.55 (95% CI 2.93-4.31) for men and 4.18 (95% CI 3.43-5.09) for women. DISCUSSION/ CONCLUSION: The prevalence of hypertriglyceridemic waist has reached an alarming level and is closely associated with increased risk of T2DM in the general population, particularly among women and among brown-skinned men and women.
INTRODUCTION: A meta-analysis of studies assessing the prevalence of hypertriglyceridemic waist and an association with risk of type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: PubMed, EMBASE, Web of Science, CNKI, CQVIP and Wanfang databases were searched for studies of the prevalence of hypertriglyceridemic waist or association with risk of T2DM. Reference lists of each original article were also searched. A random-effects model was used to synthesize the combined prevalence and odds ratios. Publication bias and substantial heterogeneity were examined. RESULTS: Twenty-five eligible studies involving 93 194 participants (93 194 for prevalence and 34 199 for odds ratios): 17 articles of prevalence, and 8 of both prevalence and risk of T2DM. Prevalence of hypertriglyceridemic waist ranged from 4% to 47%, with pooled prevalence of 18% (95% CI 13-23%), overall: 18% (95% CI 13-23%) for men and 19% (95% CI 13-24%) for women. Odds ratios ranged from 2.8 to 9.6 for T2MD in overall, with pooled odds ratios of 4.18 (95% CI 3.55-4.92), overall: 3.55 (95% CI 2.93-4.31) for men and 4.18 (95% CI 3.43-5.09) for women. DISCUSSION/ CONCLUSION: The prevalence of hypertriglyceridemic waist has reached an alarming level and is closely associated with increased risk of T2DM in the general population, particularly among women and among brown-skinned men and women.
Authors: Priscila Ribas de Farias Costa; Ana Marlúcia Oliveira Assis; Carla de Magalhães Cunha; Emile Miranda Pereira; Gabriela Dos Santos de Jesus; Lais Eloy Machado da Silva; Wilanne Pinheiro de Oliveira Alves Journal: Arq Bras Cardiol Date: 2017-05-25 Impact factor: 2.000
Authors: José Castela Forte; Pytrik Folkertsma; Rahul Gannamani; Sridhar Kumaraswamy; Sarah Mount; Tom J de Koning; Sipko van Dam; Bruce H R Wolffenbuttel Journal: J Pers Med Date: 2021-12-07