Literature DB >> 26417488

Photoacoustic imaging of salivary glands.

Laurie J Rich1, Mukund Seshadri2.   

Abstract

In this work, we utilized photoacoustic imaging (PAI) with co-registered ultrasound (US) to non-invasively assess salivary gland function in vivo. A significant increase in salivary gland oxygen saturation was observed on PAI within minutes after gustatory stimulation of healthy mice reflective of the hyperemic response associated with secretion of saliva. Good correlation was seen between PAI and Doppler sonography. Salivary adenoid cystic carcinomas showed higher oxygen saturation compared to surrounding salivary gland tissue. Our results demonstrate the potential clinical utility of PAI for visualization of salivary gland physiology and pathology.

Entities:  

Keywords:  (170.3880) Medical and biological imaging; (170.4580) Optical diagnostics for medicine; (170.4940) Otolaryngology; (170.5120) Photoacoustic imaging; (170.7170) Ultrasound

Year:  2015        PMID： 26417488      PMCID： PMC4574644          DOI： 10.1364/BOE.6.003157

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


  24 in total

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Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-01       Impact factor: 7.038

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Authors:  Andrew Needles; Andrew Heinmiller; John Sun; Catherine Theodoropoulos; David Bates; Desmond Hirson; Melissa Yin; F Stuart Foster
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2013-05       Impact factor: 2.725
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Authors:  Robert C McDonald
Journal:  J Med Device       Date:  2022-02-03       Impact factor: 0.582

2.  Dynamic photoacoustic imaging of neurovascular coupling in salivary glands.

Authors:  Laurie J Rich; Eftekhar Rajab Bolookat; Mukund Seshadri
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  2 in total

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