Literature DB >> 2641706

Hemophagocytosis and acute monoblastic leukemia.

L Russell1, N J Shaw, O B Eden.   

Abstract

A 16-month-old girl presented with hepatosplenomegaly and pancytopenia. Bone marrow aspiration showed a florid increase in macrophages with marked hemophagocytosis. She subsequently improved spontaneously with no therapeutic intervention, but 2 months later presented with frank acute monoblastic leukemia. This case illustrates the difficulties in classifying malignancies of the monocyte-macrophage lineage and how hemophagocytosis can be the presenting feature of a range of diseases.

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Year:  1989        PMID： 2641706     DOI： 10.3109/08880018909034309

Source DB:  PubMed          Journal:  Pediatr Hematol Oncol        ISSN： 0888-0018            Impact factor:   1.969


  2 in total

1.  Progression, transformation, and unusual manifestations of myelodysplastic syndromes and myelodysplastic-myeloproliferative neoplasms: lessons learned from the XIV European Bone Marrow Working Group Course 2019.

Authors:  Konnie Hebeda; Ludmila Boudova; Christine Beham-Schmid; Attilio Orazi; Hans-Michael Kvasnicka; Umberto Gianelli; Alexandar Tzankov
Journal:  Ann Hematol       Date:  2020-10-31       Impact factor: 3.673

2.  Hemophagocytic syndrome in children with acute monoblastic leukemia-another cause of fever of unknown origin.

Authors:  H Lackner; M G Seidel; V Strenger; P Sovinz; W Schwinger; M Benesch; D Sperl; C Urban
Journal:  Support Care Cancer       Date:  2013-08-24       Impact factor: 3.603
  2 in total

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