Shuxian Xu1,2, Yuli Huang3, Jiping Xiao4, Wenjing Zhu4, Lulu Wang5, Hongfeng Tang3, Yunzhao Hu3, Tiebang Liu2. 1. a Shenzhen Psychiatric College, Anhui Medical University , Shenzhen, Guangdong , PR China. 2. b Department of Psychiatry , Shenzhen Key Laboratory of Psychological Health Center , Shenzhen, Guangdong , PR China. 3. c Department of Cardiology , the First People's Hospital of Shunde (the Affiliated Hospital at Shunde, Southern Medical University) , Foshan, Guangdong , China. 4. d Department of Medical Psychology , Anhui Medical University , Hefei, Anhui , PR China. 5. e School of Nursing, Anhui Medical University , Hefei, Anhui , PR China.
Abstract
BACKGROUND: Studies about work stress and the risk of coronary heart disease (CHD) have yielded inconsistent results. This meta-analysis aimed to investigate the association between job strain and the risk of CHD. METHODS: We searched PubMed and Embase databases for studies reporting data on job strain and the risk of CHD. Studies were included if they reported multiple-adjusted relative risk (RR) with 95% confidence interval (CI) with respect to CHD from job strain. RESULTS: Fourteen prospective cohort studies comprising 232,767 participants were included. The risk of CHD was increased in high-strain (RR 1.26; 95% CI 1.12-1.41) and passive jobs (RR 1.14; 95% CI 1.02-1.29) but not in active jobs (RR 1.09; 95% CI 0.97-1.22), when compared with low-strain group. The increased risk of CHD in high-strain and passive jobs was mainly driven by studies with a follow-up duration of ≥ 10 years. Neither the low-control (RR 1.06; 95% CI 0.93-1.19) nor high-demand (RR 1.13; 95% CI 0.97-1.32) dimension was independently associated with the risk of CHD. CONCLUSIONS: Individuals with high-strain and passive jobs were more likely to experience a CHD event. Intervention programs incorporating individual and organizational levels are crucial for reducing job strain and the risk of CHD.
BACKGROUND: Studies about work stress and the risk of coronary heart disease (CHD) have yielded inconsistent results. This meta-analysis aimed to investigate the association between job strain and the risk of CHD. METHODS: We searched PubMed and Embase databases for studies reporting data on job strain and the risk of CHD. Studies were included if they reported multiple-adjusted relative risk (RR) with 95% confidence interval (CI) with respect to CHD from job strain. RESULTS: Fourteen prospective cohort studies comprising 232,767 participants were included. The risk of CHD was increased in high-strain (RR 1.26; 95% CI 1.12-1.41) and passive jobs (RR 1.14; 95% CI 1.02-1.29) but not in active jobs (RR 1.09; 95% CI 0.97-1.22), when compared with low-strain group. The increased risk of CHD in high-strain and passive jobs was mainly driven by studies with a follow-up duration of ≥ 10 years. Neither the low-control (RR 1.06; 95% CI 0.93-1.19) nor high-demand (RR 1.13; 95% CI 0.97-1.32) dimension was independently associated with the risk of CHD. CONCLUSIONS: Individuals with high-strain and passive jobs were more likely to experience a CHD event. Intervention programs incorporating individual and organizational levels are crucial for reducing job strain and the risk of CHD.
Entities:
Keywords:
Coronary heart disease; job strain; meta-analysis; work stress
Authors: Gisoo Alizadeh; Kamal Gholipour; Saber Azami-Aghdash; Reza Dehnavieh; Mohammad Asghari JafarAbadi; Mehrdad Azmin; Rahim Khodayari-Zarnaq Journal: Int J Prev Med Date: 2022-04-27
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