L Boeri1, P Capogrosso1,2, E Ventimiglia1,2, A Serino1, G La Croce1,2, A Russo1,2, G Castagna1,2, R Scano1, A Briganti1,2,3, R Damiano3, F Montorsi1,2, A Salonia1,2. 1. Division of Experimental Oncology/Unit of Urology, URI-Urological Research Institute, University Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy. 2. Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy. 3. Research Doctorate Program in Urology, Magna Graecia University, Catanzaro, Italy.
Abstract
BACKGROUND: Prevalence of and severity of lower urinary tract symptoms (LUTS) according to male sexual orientation have been scantly analysed. We aimed to assess the prevalence and severity of LUTS in a cohort of Caucasian-European men who have sex with men seeking medical help for uroandrologic reasons other than LUTS. METHODS: Data from 949 consecutive individuals in an outpatient setting were analysed. Severity of LUTS was measured with the International Prostate Symptom Score (IPSS). Men with storage symptoms scored 1-3 and ⩾ 4 (of 15), and voiding symptoms scored 1-4 and ⩾ 5 (of 20) were considered as having mild and moderate-to-severe symptoms, respectively. For individual symptoms, patients with scores ⩾ 1 were deemed symptomatic (according to Apostolidis et al.(15)). Descriptive statistics and logistic regression models tested the association between LUTS and sexual orientation. RESULTS: Complete data were available for 213 (22.4%) men who have sex with men (MSM) and 736 (77.6%) heterosexuals (mean age (s.d.): 41.0 (12.2) vs 39.9 (12.1) years). Compared with heterosexuals, MSM reported higher rates of total IPSS scores suggestive of moderate (21.6% vs 20%) and severe LUTS (3.8% vs 2.4%) (P=0.004). Similarly, MSM showed higher rates of mild (48.8% vs 45.2%) and moderate-to-severe (39.4% vs 30.4%) storage symptoms (all P<0.001), and of mild (45.1% vs 34.8%) and moderate-to-severe (20.2% vs 19.2%) voiding symptoms (all P<0.01). MSM status was an independent predictor of mild voiding symptoms (odds ratio (OR): 1.40; P=0.004), moderate-to-severe storage symptoms (OR: 1.40; P=0.04) and severe total IPSS (OR: 1.49; P=0.03), after adjusting for other variables. CONCLUSIONS: These findings suggest a higher prevalence and severity of LUTS in MSM compared with heterosexual men seeking medical help for uroandrologic reasons other than LUTS.
BACKGROUND: Prevalence of and severity of lower urinary tract symptoms (LUTS) according to male sexual orientation have been scantly analysed. We aimed to assess the prevalence and severity of LUTS in a cohort of Caucasian-European men who have sex with men seeking medical help for uroandrologic reasons other than LUTS. METHODS: Data from 949 consecutive individuals in an outpatient setting were analysed. Severity of LUTS was measured with the International Prostate Symptom Score (IPSS). Men with storage symptoms scored 1-3 and ⩾ 4 (of 15), and voiding symptoms scored 1-4 and ⩾ 5 (of 20) were considered as having mild and moderate-to-severe symptoms, respectively. For individual symptoms, patients with scores ⩾ 1 were deemed symptomatic (according to Apostolidis et al.(15)). Descriptive statistics and logistic regression models tested the association between LUTS and sexual orientation. RESULTS: Complete data were available for 213 (22.4%) men who have sex with men (MSM) and 736 (77.6%) heterosexuals (mean age (s.d.): 41.0 (12.2) vs 39.9 (12.1) years). Compared with heterosexuals, MSM reported higher rates of total IPSS scores suggestive of moderate (21.6% vs 20%) and severe LUTS (3.8% vs 2.4%) (P=0.004). Similarly, MSM showed higher rates of mild (48.8% vs 45.2%) and moderate-to-severe (39.4% vs 30.4%) storage symptoms (all P<0.001), and of mild (45.1% vs 34.8%) and moderate-to-severe (20.2% vs 19.2%) voiding symptoms (all P<0.01). MSM status was an independent predictor of mild voiding symptoms (odds ratio (OR): 1.40; P=0.004), moderate-to-severe storage symptoms (OR: 1.40; P=0.04) and severe total IPSS (OR: 1.49; P=0.03), after adjusting for other variables. CONCLUSIONS: These findings suggest a higher prevalence and severity of LUTS in MSM compared with heterosexual men seeking medical help for uroandrologic reasons other than LUTS.
Authors: Benjamin N Breyer; Eric Vittinghoff; Stephen K Van Den Eeden; Bradley A Erickson; Alan W Shindel Journal: Urology Date: 2011-10-02 Impact factor: 2.649
Authors: Jennifer L St Sauver; Debra J Jacobson; Michaela E McGree; Cynthia J Girman; Michael M Lieber; Steven J Jacobsen Journal: Urology Date: 2008-03 Impact factor: 2.649
Authors: Jennifer L St Sauver; Aruna V Sarma; Debra J Jacobson; Michaela E McGree; Michael M Lieber; Cynthia J Girman; Ajay Nehra; Steven J Jacobsen Journal: Am J Epidemiol Date: 2009-04-24 Impact factor: 4.897
Authors: Limin Mao; David J Templeton; June Crawford; John Imrie; Garrett P Prestage; Andrew E Grulich; Basil Donovan; John M Kaldor; Susan C Kippax Journal: J Sex Med Date: 2008-04-15 Impact factor: 3.802
Authors: Amy Cinar; Susan A Hall; Carol L Link; Steven A Kaplan; Zoe S Kopp; Claus G Roehrborn; Raymond C Rosen Journal: BJU Int Date: 2008-05 Impact factor: 5.588
Authors: B R Simon Rosser; Shanda L Hunt; Benjamin D Capistrant; Nidhi Kohli; Badrinath R Konety; Darryl Mitteldorf; Michael W Ross; Kristine M Talley; William West Journal: Curr Sex Health Rep Date: 2019-11-08