| Literature DB >> 26414864 |
Murilo S Abreu1, Ana Cristina V Giacomini2, Gessi Koakoski3, Thiago A Oliveira4, Darlan Gusso5, Bernardo Baldisserotto6, Leonardo J G Barcellos7.
Abstract
The presence of fluoxetine in aquatic environments has been reported for decades. Here, we investigate the effects of exposure to fluoxetine on the stress response and osmoregulation in zebrafish. We show that stress response alters osmoregulation and that fluoxetine inhibits these stress-related changes in osmoregulation. The results suggest that the presence of fluoxetine in aquatic ecosystems can cause changes in response to stress and osmoregulation in fish.Entities:
Keywords: Cortisol; Danio rerio; Homeostasis; Osmoregulation; Psychotropic drug; SSRI
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Year: 2015 PMID: 26414864 DOI: 10.1016/j.etap.2015.09.001
Source DB: PubMed Journal: Environ Toxicol Pharmacol ISSN: 1382-6689 Impact factor: 4.860