Literature DB >> 26414690

Hypoalbuminemia at admission is associated with increased incidence of in-hospital complications in geriatric trauma patients.

Tabitha Garwe1, Roxie M Albrecht2, Julie A Stoner3, Stephanie Mitchell2, Prasenjeet Motghare3.   

Abstract

BACKGROUND: Elderly patients are at an increased risk of protein-energy malnutrition (PEM) which increases the risk of morbidity/mortality. We evaluated the association between hypoalbuminemia at the time of emergency department (ED) admission and in-hospital complications among geriatric trauma patients.
METHODS: This was an ambidirectional cohort study of geriatric (≥55 years) trauma patients treated at a Level I trauma center between May 2013 and March 2014. The exposure of interest was albumin level at ED admission (<3.6 g/dL [PEM] or ≥3.6 g/dL (No PEM)]. The outcome of interest was 30-day incidence of complications.
RESULTS: A total of 130 patients met study eligibility. Of these, 85 (65%) patients were in the PEM group. After adjusting for tube feeding and injury severity score, PEM at admission was associated with a 2-fold increase in the risk of 30-day overall hospital complications (hazard ratio 2.1, 95% confidence interval 1.1 to 3.8).
CONCLUSION: Serum albumin level at ED admission, but not prealbumin level, is a significant predictor of in-hospital complications in geriatric trauma patients.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Complications; Geriatric trauma; Hypoalbuminemia; In-hospital; Protein–energy malnutrition

Mesh:

Year:  2015        PMID: 26414690      PMCID: PMC4821821          DOI: 10.1016/j.amjsurg.2015.06.013

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


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