Literature DB >> 26414453

Updated evidence on adjuvant treatments for gastric cancer.

Mitsuro Kanda1, Yasuhiro Kodera1, Junichi Sakamoto2.   

Abstract

Gastric cancer is one of the main causes of cancer-related deaths worldwide. Even when diagnosed as a localized disease and resected with the intent to cure, recurrences frequently arise due to undetected or invisible micrometastases. Importantly, several proposed multimodal strategies to eliminate micrometastases have met some clinical success. However, while pivotal Phase III clinical trials comparing adjuvant therapies with surgery alone have confirmed the overall benefit of adjunctive treatments in patients with locally advanced gastric cancer, further improvement in postoperative outcomes is required, particularly in stage III disease. This review presents the current status of multimodal treatment strategies, with a particular focus on unresolved issues, based on updated literature searches and analysis of clinical trial databases.

Entities:  

Keywords:  adjuvant; gastric cancer; molecular targeting therapy; neoadjuvant; prognostic factor; radiation

Mesh：

Substances：

Year:  2015        PMID： 26414453     DOI： 10.1586/17474124.2015.1094373

Source DB:  PubMed          Journal:  Expert Rev Gastroenterol Hepatol        ISSN： 1747-4124            Impact factor:   3.869


  14 in total

1.  Proposal of a Scoring Scale to Estimate Risk of the Discontinuation of S-1 Adjuvant Monotherapy in Patients with Stage II to III Gastric Cancer: A Multi-Institutional Dataset Analysis.

Authors:  Akimitsu Iizuka; Mitsuro Kanda; Seiji Ito; Yoshinari Mochizuki; Hitoshi Teramoto; Kiyoshi Ishigure; Toshifumi Murai; Takahiro Asada; Akiharu Ishiyama; Hidenobu Matsushita; Chie Tanaka; Daisuke Kobayashi; Michitaka Fujiwara; Kenta Murotani; Yasuhiro Kodera
Journal:  World J Surg       Date:  2019-08       Impact factor: 3.352

2.  Preoperative Albumin-Bilirubin Grade Predicts Recurrences After Radical Gastrectomy in Patients with pT2-4 Gastric Cancer.

Authors:  Mitsuro Kanda; Chie Tanaka; Daisuke Kobayashi; Hiroaki Uda; Kenichi Inaoka; Yuri Tanaka; Masamichi Hayashi; Naoki Iwata; Suguru Yamada; Tsutomu Fujii; Hiroyuki Sugimoto; Kenta Murotani; Michitaka Fujiwara; Yasuhiro Kodera
Journal:  World J Surg       Date:  2018-03       Impact factor: 3.352

Review 3.  Molecular mechanisms of peritoneal dissemination in gastric cancer.

Authors:  Mitsuro Kanda; Yasuhiro Kodera
Journal:  World J Gastroenterol       Date:  2016-08-14       Impact factor: 5.742

4.  Number of retrieved lymph nodes is an independent prognostic factor after total gastrectomy for patients with stage III gastric cancer: propensity score matching analysis of a multi-institution dataset.

Authors:  Shogo Hayashi; Mitsuro Kanda; Seiji Ito; Yoshinari Mochizuki; Hitoshi Teramoto; Kiyoshi Ishigure; Toshifumi Murai; Takahiro Asada; Akiharu Ishiyama; Hidenobu Matsushita; Chie Tanaka; Daisuke Kobayashi; Michitaka Fujiwara; Kenta Murotani; Yasuhiro Kodera
Journal:  Gastric Cancer       Date:  2018-11-27       Impact factor: 7.370

Review 5.  Emerging evidence of the molecular landscape specific for hematogenous metastasis from gastric cancer.

Authors:  Dai Shimizu; Mitsuro Kanda; Yasuhiro Kodera
Journal:  World J Gastrointest Oncol       Date:  2018-06-15

Review 6.  Recent updates in perioperative chemotherapy and recurrence pattern of gastric cancer.

Authors:  Shingo Kanaji; Satoshi Suzuki; Yoshiko Matsuda; Hiroshi Hasegawa; Masashi Yamamoto; Kimihiro Yamashita; Taro Oshikiri; Takeru Matsuda; Tetsu Nakamura; Yasuo Sumi; Yoshihiro Kakeji
Journal:  Ann Gastroenterol Surg       Date:  2018-08-29

7.  Pathological tumor infiltrative pattern and sites of initial recurrence in stage II/III gastric cancer: Propensity score matching analysis of a multi-institutional dataset.

Authors:  Nobuhiko Nakagawa; Mitsuro Kanda; Seiji Ito; Yoshinari Mochizuki; Hitoshi Teramoto; Kiyoshi Ishigure; Toshifumi Murai; Takahiro Asada; Akiharu Ishiyama; Hidenobu Matsushita; Chie Tanaka; Daisuke Kobayashi; Michitaka Fujiwara; Kenta Murotani; Yasuhiro Kodera
Journal:  Cancer Med       Date:  2018-11-08       Impact factor: 4.452

8.  Albumin-Bilirubin Score Predicts Tolerability to Adjuvant S-1 Monotherapy after Curative Gastrectomy.

Authors:  Takashi Miwa; Mitsuro Kanda; Chie Tanaka; Daisuke Kobayashi; Masamichi Hayashi; Suguru Yamada; Goro Nakayama; Masahiko Koike; Yasuhiro Kodera
Journal:  J Gastric Cancer       Date:  2019-04-22       Impact factor: 3.720

9.  Nutritional predictors for postoperative short-term and long-term outcomes of patients with gastric cancer.

Authors:  Mitsuro Kanda; Akira Mizuno; Chie Tanaka; Daisuke Kobayashi; Michitaka Fujiwara; Naoki Iwata; Masamichi Hayashi; Suguru Yamada; Goro Nakayama; Tsutomu Fujii; Hiroyuki Sugimoto; Masahiko Koike; Hideki Takami; Yukiko Niwa; Kenta Murotani; Yasuhiro Kodera
Journal:  Medicine (Baltimore)       Date:  2016-06       Impact factor: 1.889

10.  Integrated multigene expression panel to prognosticate patients with gastric cancer.

Authors:  Mitsuro Kanda; Kenta Murotani; Haruyoshi Tanaka; Takashi Miwa; Shinichi Umeda; Chie Tanaka; Daisuke Kobayashi; Masamichi Hayashi; Norifumi Hattori; Masaya Suenaga; Suguru Yamada; Goro Nakayama; Michitaka Fujiwara; Yasuhiro Kodera
Journal:  Oncotarget       Date:  2018-04-10
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.