Literature DB >> 26413162

Phosphatidic acid: a new therapeutic lead to suppress hepatic glucose production.

Anil K Agarwal1, Shireesha Sankella1.   

Abstract

Entities:  

Keywords:  gluconeogenesis; hepatic steatosis; insulin resistance; lipodystrophy; lysophosphatidic acid; phosphatidic acid; rare disease

Year:  2014        PMID： 26413162      PMCID： PMC4582667          DOI： 10.2217/dmt.14.29

Source DB:  PubMed          Journal:  Diabetes Manag (Lond)        ISSN： 1758-1907


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  15 in total

Review 1.  Lysophospholipid acyltransferases: 1-acylglycerol-3-phosphate O-acyltransferases. From discovery to disease.

Authors:  Anil K Agarwal
Journal:  Curr Opin Lipidol       Date:  2012-08       Impact factor: 4.776

2.  Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.

Authors:  Chongben Zhang; Angela A Wendel; Matthew R Keogh; Thurl E Harris; Jie Chen; Rosalind A Coleman
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-17       Impact factor: 11.205

Review 3.  Mechanisms of diabetic complications.

Authors:  Josephine M Forbes; Mark E Cooper
Journal:  Physiol Rev       Date:  2013-01       Impact factor: 37.312

Review 4.  Clinical review#: Lipodystrophies: genetic and acquired body fat disorders.

Authors:  Abhimanyu Garg
Journal:  J Clin Endocrinol Metab       Date:  2011-08-24       Impact factor: 5.958

5.  Human 1-acylglycerol-3-phosphate O-acyltransferase isoforms 1 and 2: biochemical characterization and inability to rescue hepatic steatosis in Agpat2(-/-) gene lipodystrophic mice.

Authors:  Anil K Agarwal; Suja Sukumaran; Víctor A Cortés; Katie Tunison; Dario Mizrachi; Shireesha Sankella; Robert D Gerard; Jay D Horton; Abhimanyu Garg
Journal:  J Biol Chem       Date:  2011-08-27       Impact factor: 5.157

6.  AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34.

Authors:  Anil K Agarwal; Elif Arioglu; Salome De Almeida; Nurullah Akkoc; Simeon I Taylor; Anne M Bowcock; Robert I Barnes; Abhimanyu Garg
Journal:  Nat Genet       Date:  2002-04-22       Impact factor: 38.330

Review 7.  Novel therapies for the management of type 2 diabetes mellitus: part 1. pramlintide and bromocriptine-QR.

Authors:  George Grunberger
Journal:  J Diabetes       Date:  2013-06       Impact factor: 4.006

8.  Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy.

Authors:  Víctor A Cortés; David E Curtis; Suja Sukumaran; Xinli Shao; Vinay Parameswara; Shirya Rashid; Amy R Smith; Jimin Ren; Victoria Esser; Robert E Hammer; Anil K Agarwal; Jay D Horton; Abhimanyu Garg
Journal:  Cell Metab       Date:  2009-02       Impact factor: 27.287

Review 9.  Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways.

Authors:  Anil K Agarwal; Abhimanyu Garg
Journal:  Trends Endocrinol Metab       Date:  2003-07       Impact factor: 12.015

10.  Global estimates of undiagnosed diabetes in adults.

Authors:  Jessica Beagley; Leonor Guariguata; Clara Weil; Ayesha A Motala
Journal:  Diabetes Res Clin Pract       Date:  2013-12-01       Impact factor: 5.602
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