| Literature DB >> 26412858 |
Pritaporn Kingkaew1, Pitsaphun Werayingyong2, San San Aye3, Nilar Tin4, Alaka Singh5, Phone Myint3, Yot Teerawattananon2.
Abstract
Reducing child and maternal mortality in order to meet the health-related Millennium Development Goals (MDGs) 4 and 5 remains a major challenge in Myanmar. Inadequate care during pregnancy and labour plays an important role in the maternal mortality rate in Myanmar. A Maternal and Child Health (MCH) Voucher Scheme comprising a subsidization for pregnant women to receive four antenatal care (ANC), delivery and postnatal care (PNC) free-of-charge was planned to help women overcome financial barriers in addition to raising awareness of ANC and delivery with skilled birth attendants (SBA), which can reduce the rate of maternal and neonatal death. This study is part of an ex-ante evaluation of a feasibility study of the MCH Voucher Scheme. A cost-utility analysis was conducted using a decision tree model to assess the cost per disability-adjusted life years (DALYs) averted from the MCH Voucher Scheme compared with the current situation. Most input parameters were obtained from Myanmar context. From the base-case analysis, where the financial burden on households was fully subsidized, the MCH Voucher Scheme increased utilization for ANC from 73% up to 93% and for delivery from SBAs from 51% up to and 71%, respectively; hence, it is considered to be very cost-effective with an incremental cost-effectiveness ratio of 381 027 kyats per DALY averted (2010, price year). From the probabilistic sensitivity analysis, the MCH Voucher Scheme had a 52% chance of being a cost-effective option at 1 GDP per capita threshold compared to the current situation. Given that the Voucher Scheme is currently being implemented in one township in Myanmar as a result of this study, ongoing evaluation of the effectiveness and cost-effectiveness of this scheme is warranted.Entities:
Keywords: Cost-utility analysis; decision analysis model; demand side financing; maternal and child health; obstetric labor; prenatal care; skilled birth attendant; traditional birth attendant
Mesh:
Year: 2015 PMID: 26412858 PMCID: PMC4986242 DOI: 10.1093/heapol/czv090
Source DB: PubMed Journal: Health Policy Plan ISSN: 0268-1080 Impact factor: 3.344
Figure 1.Comparing the maternal mortality ratio (per 1000 live births) among different sources of data
Figure 2.Decision tree illustrating the pathway of the MCH Voucher Scheme
Model parameters, values, parameter distributions and data sources used in the decision tree model
| Parameters | Mean (SE) | Parameter distribution | Data source |
|---|---|---|---|
| Baseline probability of seeking ANC with SBAs | 0.73 (0.03) | Beta | Survey |
| Baseline probability of delivery with SBAs | 0.51 (0.04) | Beta | Survey |
| Probability of receiving ANC at home | 0.21 (0.03) | Beta | Survey |
| Probability of delivery in health facility | 0.19 (0.04) | Beta | Survey |
| Proportion of high-risk pregnancy | 15% (0.42%) | Beta | ( |
| Maternal mortality rate (per 1000 live births) | 3.16 (0.7) | Beta | ( |
| Maternal morbidity rate (per 1000 live births) | 31.6 | Beta | Expert opinion |
| Neonatal mortality rate (per 1000 live births) | 16.13 | Beta | (Ministry of Health 2010) |
| Low birth weight infant (per 1000 live births) | 150 | Beta | (Ministry of Health 2010) |
| Odd ratio of maternal mortality, high-risk | 9.3 (0.87) | Gamma | ( |
| Relative risk of maternal morbidity, any complications | 1.82 | Gamma | ( |
| Relative risk of perinatal death, high risk | 1.56 (0.39) | Gamma | ( |
| Relative risk of low birth weight, high risk | 1.97 (0.28) | Gamma | ( |
| Relative risk of maternal mortality, ANC with non-SBA | 1.18 (0.30) | Gamma | |
| Relative risk of maternal morbidity, ANC with non-SBA | 1.18 (0.30) | Gamma | Expert opinion |
| Relative risk of neonatal mortality, inadequate ANC | 1.42 (0.04) | Log normal | ( |
| Relative risk of low-birth weight infants, ANC with non-SBA | 2.0 | Gamma | Expert opinion |
| Relative risk of maternal mortality, deliver with non-SBA | 1.94 (0.62) | Gamma | |
| Relative risk of maternal morbidity, deliver with non-SBA | 1.94 (0.62) | Gamma | Expert opinion |
| Relative risk of neonatal mortality, deliver with non-SBAs | 2.7 (1.35) | Gamma | ( |
| Cost of treating mother who has complications | 127 964 (9950) | Gamma | ( |
| Cost of treating LBW new born | 150 010 | Gamma | ( |
| Antenatal care at township hospital level | Gamma | Survey | |
| - 1st visit | 16,355 (454) | ||
| - Subsequent visit | 3,915 (234) | ||
| Antenatal care at MCH hospital level | Gamma | Survey | |
| - 1st visit | 16 895 (1521) | ||
| - Subsequent visit | 3983 (948) | ||
| Antenatal care at station hospital level | Gamma | Survey | |
| - 1st visit | 22 988 (6528) | ||
| - Subsequent visit | 6965 (3225) | ||
| Antenatal care at sub-centre level | Gamma | Survey | |
| - 1st visit | 16 441 (371) | ||
| - Subsequent visit | 3935 (367) | ||
| Delivery at township hospital | 38 953 (15 291) | Gamma | Survey |
| Delivery at MCH hospital | 10 631 (5571) | Gamma | Survey |
| Delivery at station hospital | 19 460 (5101) | Gamma | Survey |
| Delivery at sub-centre | 15 039 (1335) | Gamma | Survey |
| Antenatal care received from traditional birth attendants | Gamma | Survey | |
| - Cost of antenatal care | 500 (387) | ||
| - Transportation cost | 667 (494) | ||
| Antenatal care received from SBA s at home | Gamma | Survey | |
| - Cost of antenatal care | 436 (160) | ||
| - Transportation cost | 427 (67) | ||
| Antenatal care received from SBAs at health facility | Gamma | Survey | |
| - Cost of antenatal care | 1140 (197) | ||
| - Transportation cost | 427 (67) | ||
| - Productivity loss | 535 (137) | ||
| Delivery received from traditional birth attendants | Gamma | Survey | |
| - Direct medical cost | 12 239 | ||
| ✓ Fee to traditional birth attendants | 9097 (1022) | ||
| ✓ Fee to anyone else | 1435 (608) | ||
| ✓ Gifts for traditional birth attendants | 335 (152) | ||
| ✓ Cost of drugs/supplies purchased from government health facilities | 581 (490) | ||
| ✓ Cost of drugs/supplies purchased outside government health facilities | 661 (240) | ||
| ✓ Clean delivery kits | 129 (129) | ||
| - Direct non-medical cost | |||
| ✓ Food | 903 (644) | ||
| - Productivity loss of accompanying person | 15 081 (3074) | ||
| Delivery received from SBAs at home | Gamma | Survey | |
| - Direct medical cost | 18 115 | ||
| ✓ Fee to health professional | 13 344 (1227) | ||
| ✓ Fee to anyone else | 1148 (345) | ||
| ✓ Gifts for staff | 577 (226) | ||
| ✓ Cost of drugs/supplies purchased from government health facilities | 833 (560) | ||
| ✓ Cost of drugs/supplies purchased outside government health facilities | 2021 (616) | ||
| ✓ Clean delivery kits | 192 (139) | ||
| - Direct non-medical cost | |||
| ✓ Food | 565 (226) | ||
| - Productivity loss of accompanying person | 13 579 (2815) | ||
| Delivery received from SBAs at health facility | Gamma | Survey | |
| - Direct medical cost | 25 111 | ||
| ✓ Registration fee | 56 (25) | ||
| ✓ Fee to health professionals | 15 167 (4647) | ||
| ✓ Gifts for staff | 944 (659) | ||
| ✓ Cost of drugs/supplies purchased from government health facilities | 7778 (2049) | ||
| ✓ Cost of drugs/supplies purchased outside government health facilities | 1167 (860) | ||
| - Direct non-medical cost | 26 578 | ||
| ✓ Accommodation for pregnant women | 1694 (668) | ||
| ✓ Accommodation for accompanying person | 1389 (1389) | ||
| ✓ Food | 11 278 (3647) | ||
| ✓ Washing clothes or cleansing | 828 (364) | ||
| ✓ Transportation cost to health facilities | 11 389 (2926) | ||
| - Productivity loss of accompanying person | 15 689 (4624) | ||
| 1340 | Gamma | ||
| Life expectancy at birth | 54.40 | ( | |
| Life expectancy at 28 years old | 42.80 | ( | |
| Vary from low birth weight to birth asphyxia and birth trauma | 0.106 | Beta | ( |
| (0.372–0.106) | |||
| Vary from stress incontinence to obstructed labour | 0.093 | Beta | ( |
| 0.43–0.025 | |||
MCH = Maternal and Child Health Centre; SE = standard error.
aCalculation based on data from the Nationwide Cause Specific Maternal Mortality Survey.
bAssume standard error equals to mean values.
cBased on the actual voucher production.
Conditional probabilities for maternal mortality and maternal morbidity given pregnancy risk, antenatal care and delivery by skilled attendants
| Conditions | Conditional probabilities | ||||
|---|---|---|---|---|---|
| Pregnancy | Antenatal care | Delivery | Healthy | Morbidity | Death |
| Low risk | By SBAs | By SBAs | 0.9135 | 0.0799 | 0.0066 |
| Low risk | By SBAs | By traditional birth attendants | 0.8913 | 0.1001 | 0.0086 |
| Low risk | By traditional birth attendants | By SBAs | 0.9077 | 0.0852 | 0.0071 |
| Low risk | By traditional birth attendants | By traditional birth attendants | 0.8854 | 0.1054 | 0.0091 |
| High risk | By SBAs | By SBAs | 0.8787 | 0.1030 | 0.0183 |
| High risk | By SBAs | By traditional birth attendants | 0.8564 | 0.1233 | 0.0203 |
| High risk | By traditional birth attendants | By SBAs | 0.8728 | 0.1084 | 0.0188 |
| High risk | By traditional birth attendants | By traditional birth attendants | 0.8506 | 0.1286 | 0.0209 |
Conditional probabilities for neonatal mortality and maternal morbidity given pregnancy risk, antenatal care and delivery by skilled attendants
| Conditions | Conditional probabilities | ||||
|---|---|---|---|---|---|
| Pregnancy | Antenatal care | Delivery | Healthy | Morbidity | Death |
| Low risk | By SBAs | By SBAs | 0.7128 | 0.2491 | 0.0381 |
| Low risk | By SBAs | By traditional birth attendants | 0.6979 | 0.2491 | 0.0530 |
| Low risk | By traditional birth attendants | By SBAs | 0.5887 | 0.3671 | 0.0442 |
| Low risk | By traditional birth attendants | By traditional birth attendants | 0.5738 | 0.3671 | 0.0591 |
| High risk | By SBAs | By SBAs | 0.5774 | 0.3762 | 0.0465 |
| High risk | By SBAs | By traditional birth attendants | 0.5625 | 0.3762 | 0.0614 |
| High risk | By traditional birth attendants | By SBAs | 0.4533 | 0.4942 | 0.0525 |
| High risk | By traditional birth attendants | By traditional birth attendants | 0.4384 | 0.4942 | 0.0674 |
Figure 3.The percentage of service utilization where subsidies were varied for households through the Maternal and Child Health Voucher Scheme
Costs and outcomes of the current situation of maternal and child health services and the Maternal and Child Health (MCH) Voucher Scheme
| Mother | Child | Total | |
|---|---|---|---|
| Current situation | |||
| Cost (kyats) | 73 865 | 45 003 | 118 868 |
| Life year | 42.39 | 51.75 | 94.15 |
| Disability Adjusted Life Year (DALY) | 0.41 | 2.66 | 3.08 |
| MCH Voucher Scheme | |||
| Cost (kyats) | 173 162 | 41 462 | 214 624 |
| Life year | 42.42 | 51.98 | 94.40 |
| DALY | 0.39 | 2.43 | 2.83 |
| Incremental cost (kyats) | 95 756 | ||
| Incremental life year saved | 0.2513 | ||
| Incremental DALY averted | 0.2531 | ||
| Incremental Cost Effectiveness Ratio (kyats per DALY averted) | |||
Figure 4.One-way sensitivity analysis of the incremental cost-effectiveness ratio of the Maternal and Child Health Voucher Scheme compared with current situation
Figure 5.Cost-effectiveness acceptability curves of the Maternal and Child Health Voucher Scheme by different price elasticity of demand for maternal and child health services