| Literature DB >> 264091 |
G Barile, G Sica, A Montemurro, S Iacobelli, M Corradini.
Abstract
Receptors for estrogens and progesterone have been assayed in 24 samples of normal human endometria at different phases of the menstrual cycle. In the proliferative endometrium the concentration of estrogen binding sites was significantly higher than that of progesterone receptor while, in the secretive endometrium, the concentration of estrogen receptor was low, compared to that of progesterone receptor. The highest concentration of both receptors was observed during the periovulatory period. From the correlation observed between estrogen and progesterone receptors and the levels of the respective steroids in the plasma, it is suggested that the levels of plasma estradiol or its own tissue receptor determine the synthesis of progesterone receptors in the periovulatory period.Entities:
Keywords: Biology; Comparative Studies; Endocrine System; Endometrial Effects; Endometrium; Estradiol; Estrogens; Genitalia; Genitalia, Female; Histology; Hormone Receptors--analysis; Hormones; Laboratory Procedures; Membrane Proteins; Menstrual Cycle; Menstruation; Physiology; Progestational Hormones; Progesterone; Reproduction; Research Methodology; Studies; Urogenital System; Uterus
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Year: 1979 PMID： 264091 DOI： 10.1016/0028-2243(79)90062-5
Source DB: PubMed Journal: Eur J Obstet Gynecol Reprod Biol ISSN： 0301-2115 Impact factor: 2.435