Literature DB >> 26408565

The Mode of Action for Phenobarbital-Induced Rodent Liver Tumor Formation Is not Relevant for Humans: Recent Studies With Humanized Mice.

Tomoya Yamada, Samuel M Cohen, Brian G Lake.   

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Year:  2015        PMID: 26408565     DOI: 10.1093/toxsci/kfv186

Source DB:  PubMed          Journal:  Toxicol Sci        ISSN: 1096-0929            Impact factor:   4.849


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  5 in total

Review 1.  Case examples of an evaluation of the human relevance of the pyrethroids/pyrethrins-induced liver tumours in rodents based on the mode of action.

Authors:  Tomoya Yamada
Journal:  Toxicol Res (Camb)       Date:  2018-01-16       Impact factor: 3.524

2.  Candidate genes responsible for early key events of phenobarbital-promoted mouse hepatocellular tumorigenesis based on differentiation of regulating genes between wild type mice and humanized chimeric mice.

Authors:  Ayako Ohara; Yasuhiko Takahashi; Miwa Kondo; Yu Okuda; Shuji Takeda; Masahiko Kushida; Kentaro Kobayashi; Kayo Sumida; Tomoya Yamada
Journal:  Toxicol Res (Camb)       Date:  2017-08-24       Impact factor: 3.524

3.  Sex-Differential Responses of Tumor Promotion-Associated Genes and Dysregulation of Novel Long Noncoding RNAs in Constitutive Androstane Receptor-Activated Mouse Liver.

Authors:  Nicholas J Lodato; Tisha Melia; Andy Rampersaud; David J Waxman
Journal:  Toxicol Sci       Date:  2017-09-01       Impact factor: 4.849

4.  Proteomic analysis of hepatic effects of phenobarbital in mice with humanized liver.

Authors:  Heike Sprenger; Josef Daniel Rasinger; Helen Hammer; Wael Naboulsi; Elke Zabinsky; Hannes Planatscher; Michael Schwarz; Oliver Poetz; Albert Braeuning
Journal:  Arch Toxicol       Date:  2022-07-26       Impact factor: 6.168

5.  Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development.

Authors:  G A Chappell; M M Heintz; L C Haws
Journal:  Curr Res Toxicol       Date:  2021-01-12
  5 in total

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