| Literature DB >> 26408064 |
Isaac Jonathan Pomeraniec1, Alexander Ksendzovsky1, Pearl L Yu1, John A Jane2.
Abstract
Sleep apnea represents a relative indication for posterior fossa decompression in pediatric patients with Chiari malformation type 1. Duraplasty was associated with improvement of sleep apnea in 100% of patients and dural splitting with improvement in 50% of patients. Duraplasty and dural splitting were associated with a similar reduction in tonsillar herniation on radiographic imaging of 58% (37% excluding tonsillectomy) and 35%, respectively. Longitudinal follow-up studies of patients with either neurologic deficits or severe symptoms will further elucidate the natural history of Chiari malformation type 1 and more appropriately gauge the risk-benefit tradeoff of surgical intervention.Entities:
Keywords: Chiari malformation; Dural splitting; Duraplasty; Sleep apnea
Mesh:
Year: 2015 PMID: 26408064 PMCID: PMC4584091 DOI: 10.1016/j.nec.2015.06.009
Source DB: PubMed Journal: Neurosurg Clin N Am ISSN: 1042-3680 Impact factor: 2.509