Literature DB >> 26407695

Guideline-conforming timing of invasive management in troponin-positive or high-risk ACS without persistent ST-segment elevation in German chest pain units. Urban university maximum care vs. rural regional primary care.

F Breuckmann1, F Remberg2, D Böse2, M Lichtenberg3, P Kümpers4, H Pavenstädt4, J Waltenberger5, D Fischer5.   

Abstract

AIM: This study aimed to analyze guideline adherence in the timing of invasive management for myocardial infarction without persistent ST-segment elevation (NSTEMI) in two exemplary German centers, comparing an urban university maximum care facility and a rural regional primary care facility.
METHODS: All patients diagnosed as having NSTEMI during 2013 were retrospectively enrolled in two centers: (1) site I, a maximum care center in an urban university setting, and (b) site II, a primary care center in a rural regional care setting. Data acquisition included time intervals from admission to invasive management, risk criteria, rate of intervention, and medical therapy.
RESULTS: The median time from admission to coronary angiography was 12.0 h (site I) or 17.5 h (site II; p = 0.17). Guideline-adherent timing was achieved in 88.1 % (site I) or 82.9 % (site II; p = 0.18) of cases. Intervention rates were high in both sites (site I-75.5 % vs. site II-75.3 %; p = 0.85). Adherence to recommendations of medical therapy was high and comparable between the two sites.
CONCLUSION: In NSTEMI or high-risk acute coronary syndromes without persistent ST-segment elevation, guideline-adherent timing of invasive management was achieved in about 85 % of cases, and was comparable between urban maximum and rural primary care settings. Validation by the German Chest Pain Unit Registry including outcome analysis is required.

Entities:  

Keywords:  Acute coronary syndrome; Chest pain unit; Coronary angiography; Guideline adherence; Non-ST-segment elevation myocardial infarction; Timing

Mesh:

Substances:

Year:  2015        PMID: 26407695     DOI: 10.1007/s00059-015-4354-8

Source DB:  PubMed          Journal:  Herz        ISSN: 0340-9937            Impact factor:   1.443


  27 in total

1.  High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission.

Authors:  Evangelos Giannitsis; Meike Becker; Kerstin Kurz; Georg Hess; Dietmar Zdunek; Hugo A Katus
Journal:  Clin Chem       Date:  2010-02-18       Impact factor: 8.327

2.  Coronary procedures in German hospitals: a detailed analysis for specific patient clusters.

Authors:  Kurt Bestehorn; Timm Bauer; Eckart Fleck; Maike Bestehorn; Jürgen Pauletzki; Christian Hamm
Journal:  Clin Res Cardiol       Date:  2015-01-28       Impact factor: 5.460

3.  Influence of updated guidelines on short- and long-term mortality in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS).

Authors:  B Vogel; S Hahne; I Kozanli; K Kalla; R Jarai; M Freynhofer; P Smetana; M Nürnberg; A Geppert; G Unger; K Huber
Journal:  Int J Cardiol       Date:  2011-03-29       Impact factor: 4.164

4.  Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig Immediate versus early and late PercutaneouS coronary Intervention triAl in NSTEMI (LIPSIA-NSTEMI Trial).

Authors:  Holger Thiele; Justus Rach; Norbert Klein; Dietrich Pfeiffer; Andreas Hartmann; Rainer Hambrecht; Peter Sick; Ingo Eitel; Steffen Desch; Gerhard Schuler
Journal:  Eur Heart J       Date:  2011-11-21       Impact factor: 29.983

5.  The patient's interpretation of myocardial infarction symptoms and its role in the decision process to seek treatment: the MONICA/KORA Myocardial Infarction Registry.

Authors:  Inge Kirchberger; Margit Heier; Rupert Wende; Wolfgang von Scheidt; Christa Meisinger
Journal:  Clin Res Cardiol       Date:  2012-05-23       Impact factor: 5.460

6.  Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients.

Authors:  T Killip; J T Kimball
Journal:  Am J Cardiol       Date:  1967-10       Impact factor: 2.778

Review 7.  Extended duration dual antiplatelet therapy and mortality: a systematic review and meta-analysis.

Authors:  Sammy Elmariah; Laura Mauri; Gheorghe Doros; Benjamin Z Galper; Kelly E O'Neill; Philippe Gabriel Steg; Dean J Kereiakes; Robert W Yeh
Journal:  Lancet       Date:  2014-11-16       Impact factor: 79.321

8.  Timing of percutaneous coronary intervention in troponin-negative patients with acute coronary syndrome without persistent ST-segment elevation: preliminary results and status quo in German chest pain units.

Authors:  Frank Breuckmann; Matthias Hochadel; Thomas Münzel; Evangelos Giannitsis; Thomas Voigtländer; Jochen Senges
Journal:  Crit Pathw Cardiol       Date:  2015-03

9.  The German CPU Registry: Dyspnea independently predicts negative short-term outcome in patients admitted to German Chest Pain Units.

Authors:  Kristian Hellenkamp; Harald Darius; Evangelos Giannitsis; Raimund Erbel; Michael Haude; Christian Hamm; Gerd Hasenfuss; Gerd Heusch; Harald Mudra; Thomas Münzel; Claus Schmitt; Burghard Schumacher; Jochen Senges; Thomas Voigtländer; Lars S Maier
Journal:  Int J Cardiol       Date:  2014-11-28       Impact factor: 4.164

Review 10.  [Acute thoracic pain: Chest Pain Unit - the certification campaign of the German Society of Cardiology].

Authors:  Frank Breuckmann; Felix Post; Raimund Erbel; Thomas Münzel
Journal:  Herz       Date:  2009-05       Impact factor: 1.443

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  4 in total

Review 1.  German chest pain unit registry: data review after the first decade of certification.

Authors:  Frank Breuckmann; Tienush Rassaf; Matthias Hochadel; Evangelos Giannitsis; Thomas Münzel; Jochen Senges
Journal:  Herz       Date:  2020-03-30       Impact factor: 1.443

2.  Anti-glioma action of aloe emodin: the role of ERK inhibition.

Authors:  S Mijatovic; D Maksimovic-Ivanic; J Radovic; Dj Miljkovic; Lj Harhaji; O Vuckovic; S Stosic-Grujicic; M Mostarica Stojkovic; V Trajkovic
Journal:  Cell Mol Life Sci       Date:  2005-03       Impact factor: 9.261

3.  On- versus off-hour care for patients with non-ST-segment elevation myocardial infarction in Germany : Exemplary results within the chest pain unit concept.

Authors:  F Breuckmann; F Remberg; D Böse; J Waltenberger; D Fischer; T Rassaf
Journal:  Herz       Date:  2016-05-19       Impact factor: 1.443

4.  How rapid is rapid? Exemplary results of real-life rapid rule-out troponin timing in troponin-positive acute coronary syndromes without persistent ST-segment elevation in two contrasting German chest pain unit facilities.

Authors:  Dieter Fischer; Friederike Remberg; Dirk Böse; Michael Lichtenberg; Philipp Kümpers; Pia Lebiedz; Hermann-Joseph Pavenstädt; Johannes Waltenberger; Frank Breuckmann
Journal:  Eur J Med Res       Date:  2016-03-17       Impact factor: 2.175

  4 in total

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