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Literature DB >> 26407282

Fusobacterium nucleatum Osteomyelitis in 3 Previously Healthy Children: A Case Series and Review of the Literature.

Seth W Gregory¹, Thomas G Boyce², A Noelle Larson³, Robin Patel⁴, Mary Anne Jackson⁵.

Abstract

Fusobacterium nucleatum is a rare cause of monomicrobial osteomyelitis in children. We describe the cases of 3 children with F. nucleatum osteomyelitis of the distal femoral epiphysis with concurrent septic arthritis and review 6 other cases reported in the literature. Our report emphasizes the importance of maintaining a high index of suspicion for anaerobic osteomyelitis, given its atypical presentation and the unique growth requirements of anaerobic bacteria.

Entities: Disease Species

Keywords: anaerobic osteomyelitis; epiphyseal lesion; pediatric

Mesh：

Year: 2015 PMID： 26407282 PMCID： PMC4681383 DOI： 10.1093/jpids/piv052

Source DB: PubMed Journal: J Pediatric Infect Dis Soc ISSN： 2048-7193 Impact factor: 3.164

15 in total

Review 1. Acute hematogenous osteomyelitis.

Authors: Dennis A Conrad
Journal: Pediatr Rev Date: 2010-11

2. Bone infections involving anaerobic bacteria.

Authors: R P Lewis; V L Sutter; S M Finegold
Journal: Medicine (Baltimore) Date: 1978-07 Impact factor: 1.889

3. Fusobacterium osteomyelitis in a child with sickle cell disease.

Authors: Sandra J Murray; Jay M Lieberman
Journal: Pediatr Infect Dis J Date: 2002-10 Impact factor: 2.129

4. Septic arthritis and osteomyelitis in a 10-year-old boy, caused by Fusobacterium nucleatum, diagnosed with PCR/16S ribosomal bacterial DNA amplification.

Authors: Elke Kroon; Niek A Arents; Feico Jan Halbertsma
Journal: BMJ Case Rep Date: 2012-05-11

5. Anaerobic osteomyelitis.

Authors: M J Raff; J C Melo
Journal: Medicine (Baltimore) Date: 1978-01 Impact factor: 1.889

Review 6. Anaerobic infections: update on treatment considerations.

Authors: Elisabeth Nagy
Journal: Drugs Date: 2010-05-07 Impact factor: 9.546

7. Multicenter survey of the changing in vitro antimicrobial susceptibilities of clinical isolates of Bacteroides fragilis group, Prevotella, Fusobacterium, Porphyromonas, and Peptostreptococcus species.

Authors: K E Aldridge; D Ashcraft; K Cambre; C L Pierson; S G Jenkins; J E Rosenblatt
Journal: Antimicrob Agents Chemother Date: 2001-04 Impact factor: 5.191

4. Fusobacterium nucleatum infection-induced neurodegeneration and abnormal gut microbiota composition in Alzheimer's disease-like rats.

Authors: Caixia Yan; Qilin Diao; Yuxi Zhao; Cheng Zhang; Xiaoya He; Ruijie Huang; Yan Li
Journal: Front Neurosci Date: 2022-09-16 Impact factor: 5.152

4 in total

Fusobacterium nucleatum Osteomyelitis in 3 Previously Healthy Children: A Case Series and Review of the Literature.

Review 1. Acute hematogenous osteomyelitis.

2. Bone infections involving anaerobic bacteria.

3. Fusobacterium osteomyelitis in a child with sickle cell disease.

4. Septic arthritis and osteomyelitis in a 10-year-old boy, caused by Fusobacterium nucleatum, diagnosed with PCR/16S ribosomal bacterial DNA amplification.

5. Anaerobic osteomyelitis.

Review 6. Anaerobic infections: update on treatment considerations.

7. Multicenter survey of the changing in vitro antimicrobial susceptibilities of clinical isolates of Bacteroides fragilis group, Prevotella, Fusobacterium, Porphyromonas, and Peptostreptococcus species.

Review 8. Fusobacterial infections in children.

Review 9. Joint and bone infections due to anaerobic bacteria in children.

10. Osteomyelitis of the pelvis due to Fusobacterium nucleatum.

Review 1. Fusobacterium nucleatum - symbiont, opportunist and oncobacterium.

2. Erosion of the sella turcica and pituitary expansion secondary to polymicrobial brain abscesses: a case report.

Review 3. More Than Just a Periodontal Pathogen -the Research Progress on Fusobacterium nucleatum.

4. Fusobacterium nucleatum infection-induced neurodegeneration and abnormal gut microbiota composition in Alzheimer's disease-like rats.