Literature DB >> 26407216

Hypertension in sub-Saharan Africa: a massive and increasing health disaster awaiting solution.

Norm R C Campbell1, Daniel Lemogoum2.   

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Year:  2015        PMID: 26407216      PMCID: PMC4683293     

Source DB:  PubMed          Journal:  Cardiovasc J Afr        ISSN: 1015-9657            Impact factor:   1.167


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Introduction

Increased blood pressure is the leading risk for death globally.1 While this is also true in sub-Saharan Africa, there are many hypertension issues that are unique to the region.2 A prime and important example is that in most countries in the region, population blood pressure is increasing, while in most countries in the rest of the globe, population blood pressure is decreasing.3 Currently hypertension prevalence rates in some sub-Saharan African countries are among the highest in the world, while a few short decades ago, several countries in sub-Saharan Africa had among the lowest blood pressure levels.2 Importantly, several sub-Saharan African countries still have hypertension prevalence rates below the global average, providing an important opportunity for prevention. Recently, a needs assessment of hypertension organisations in sub-Saharan Africa also showed important and different needs from hypertension organisations in other regions of the world.4,5 Dr Seedat has comprehensively outlined relevant issues in his article ‘Why is control of hypertension in sub-Saharan Africa poor?’ (page 193) He concludes by quoting Nelson Mandela ‘We must face the matter squarely … We know that we have it in ourselves as Africans to change all this’. In my opinion, defining and acknowledging the problem is the most important step, but it is also just the first step in a long journey to improving hypertension prevention and control. That the solution to hypertension in sub-Saharan Africa is within sub-Saharan Africa is another critical observation to start that journey. What are the potential next steps?

Leadership

Without strong sub-Saharan African champions who will lead and provide direction, little will change. At a recent Pan-African hypertension meeting in Douala, there were several strong hypertension champions with knowledge, vision and skill. Many other strong champions, such as Dr Seedat, reside throughout Africa. These leaders need to work together on the following actions.

Partnership

There are several important and engaged organisations related to hypertension in sub-Saharan Africa [e.g. International Forum for Hypertension Control and Prevention in Africa, African Heart Network (AHN), Pan-African Society of Hypertension, World Hypertension League African regional office and Pan-Africa Society of Cardiology (PASCAR)]. Much broader partnerships are needed. There is an urgent need to partner with governments and the World Health Organisation (WHO), who have the ability to change policies for prevention and control. The recent worldleading and strong policy to regulate a reduction in salt additives to food in South Africa is a prime example.6,7 Forming partnerships with primary care, with other non-communicable disease (NCD) groups (e.g. diabetes), and with infectious disease groups and programmes will allow a sharing of limited resources and approaches to people at health risk and this is likely to be more efficient and cost effective. The WHO PENs programme provides a template that could assist in the integration of hypertension control with NCD control.8 Civil society organisations are better placed to advocate for societal changes to address fundamental issues such as poverty, corruption and other major social issues that Dr Seedat outlined. Civil society organisations will also have a strong interest in access to medications and basic health needs Public health and epidemiological organisations are critical to assisting in advocating for improved public health policies that might prevent hypertension. Hypertension leaders need to develop the partnerships required to drive the necessary changes Dr Seedat outlined.

Strategic planning

A coalition of partner organisations needs to develop and agree to a strategic plan for hypertension prevention and control that is either independent or integrated with NCD prevention and control.9 There are several models for hypertension strategies that could be used as examples, and the Expanded Chronic Disease model can be used as a template.10-14 Recently, many African health organisations supported a fact sheet and call to action on hypertension that could form the basis of the start of a hypertension strategy.2 An African hypertension strategy needs broad input and support, as well as prioritisation of actions, based on the importance, feasibility and opportunities for implementing the actions in sub-Saharan Africa.

Learning from and sharing best practices and experiences

Sub-Saharan Africa is a unique region therefore a sharing of resources, challenges and learnings between countries within the region may be particularly important. External experiences and practices need to be cautiously examined and applied. As Dr Seedat indicated, expensive technologies and treatment may aggravate problems by using valuable and limited resources that could be used to help many versus a few people. Nevertheless some global experiences, such as the use of task-sharing and treatment algorithms, provide a promise of enhanced outcomes at lower cost, and may be adaptable. Hypertension meetings need to be structured to share best regional experiences in prevention and control.

Advocacy

Hypertension organisations in general are not in a position to make decisions that would influence hypertension prevention and control. Therefore advocacy plays a critical role. Usually advocacy is more effective aligned with partners who agree to common goals (e.g. the need for a reliable, affordable supply of medications). Advocacy needs to be a major part of the implementation of a hypertension strategy. The recent United Nations meeting where most countries signed on to improve control of hypertension by 25% by 2025, and to increase access to essential medication and technologies, represents an important advocacy opportunity.15

Conclusion

The increasing prevalence of hypertension and poor control rates in Africa represent a complex problem. A well-organised, strategic approach with a broad partnership is the best opportunity for improvement. As Dr Seedat indicates, complex societal issues and especially poverty and lack of resources make the task daunting, but emphasise the importance of partnerships, strategic approaches and advocacy. While the solution to hypertension prevention and control resides within Africa, global hypertension organisations stand supportive to provide what expertise and knowledge we have. The World Hypertension League (WHL), while resource poor, is very interested in working with sub-Saharan African health organisations. Dr Lemogoum, a board member of the WHL, has recently opened a regional office of the WHL in Cameroon. At the end of 2014, the WHL supported academic training sessions on blood pressure screening, strategic planning for reducing dietary salt, and strategic planning to control hypertension at the 7th African Scientific Meeting on Hypertension and Cardiovascular Protection, sponsored by the International Forum for Hypertension Control and Prevention in Africa in Douala, Cameroon. In 2015, with the assistance of African health organisations and experts, the WHL led the development of a fact sheet and call to action, an infogram and a region-specific needs assessment. The International Society of Hypertension supported and co-sponsored many of these resources. The WHL is strongly encouraging national organisations to develop fact sheets and calls to action and has written a manuscript instructing how to do so.16 Furthermore, the WHL has developed a template for strategic planning.10 The WHL looks forward to working with regional sub-Saharan African organisations to prevent and control hypertension.
  11 in total

Review 1.  A framework for discussion on how to improve prevention, management, and control of hypertension in Canada.

Authors:  Norm Campbell; Eric R Young; Denis Drouin; Barbara Legowski; Michael A Adams; Judi Farrell; Janusz Kaczorowski; Richard Lewanczuk; Margaret Moy Lum-Kwong; Sheldon Tobe
Journal:  Can J Cardiol       Date:  2012-01-30       Impact factor: 5.223

2.  An effective approach to high blood pressure control: a science advisory from the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and Prevention.

Authors:  Alan S Go; Mary Ann Bauman; Sallyann M Coleman King; Gregg C Fonarow; Willie Lawrence; Kim A Williams; Eduardo Sanchez
Journal:  Hypertension       Date:  2013-11-15       Impact factor: 10.190

Review 3.  Prevention and control of hypertension: developing a global agenda.

Authors:  Norm R C Campbell; Mark L Niebylski
Journal:  Curr Opin Cardiol       Date:  2014-07       Impact factor: 2.161

4.  A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

Authors:  Stephen S Lim; Theo Vos; Abraham D Flaxman; Goodarz Danaei; Kenji Shibuya; Heather Adair-Rohani; Markus Amann; H Ross Anderson; Kathryn G Andrews; Martin Aryee; Charles Atkinson; Loraine J Bacchus; Adil N Bahalim; Kalpana Balakrishnan; John Balmes; Suzanne Barker-Collo; Amanda Baxter; Michelle L Bell; Jed D Blore; Fiona Blyth; Carissa Bonner; Guilherme Borges; Rupert Bourne; Michel Boussinesq; Michael Brauer; Peter Brooks; Nigel G Bruce; Bert Brunekreef; Claire Bryan-Hancock; Chiara Bucello; Rachelle Buchbinder; Fiona Bull; Richard T Burnett; Tim E Byers; Bianca Calabria; Jonathan Carapetis; Emily Carnahan; Zoe Chafe; Fiona Charlson; Honglei Chen; Jian Shen Chen; Andrew Tai-Ann Cheng; Jennifer Christine Child; Aaron Cohen; K Ellicott Colson; Benjamin C Cowie; Sarah Darby; Susan Darling; Adrian Davis; Louisa Degenhardt; Frank Dentener; Don C Des Jarlais; Karen Devries; Mukesh Dherani; Eric L Ding; E Ray Dorsey; Tim Driscoll; Karen Edmond; Suad Eltahir Ali; Rebecca E Engell; Patricia J Erwin; Saman Fahimi; Gail Falder; Farshad Farzadfar; Alize Ferrari; Mariel M Finucane; Seth Flaxman; Francis Gerry R Fowkes; Greg Freedman; Michael K Freeman; Emmanuela Gakidou; Santu Ghosh; Edward Giovannucci; Gerhard Gmel; Kathryn Graham; Rebecca Grainger; Bridget Grant; David Gunnell; Hialy R Gutierrez; Wayne Hall; Hans W Hoek; Anthony Hogan; H Dean Hosgood; Damian Hoy; Howard Hu; Bryan J Hubbell; Sally J Hutchings; Sydney E Ibeanusi; Gemma L Jacklyn; Rashmi Jasrasaria; Jost B Jonas; Haidong Kan; John A Kanis; Nicholas Kassebaum; Norito Kawakami; Young-Ho Khang; Shahab Khatibzadeh; Jon-Paul Khoo; Cindy Kok; Francine Laden; Ratilal Lalloo; Qing Lan; Tim Lathlean; Janet L Leasher; James Leigh; Yang Li; John Kent Lin; Steven E Lipshultz; Stephanie London; Rafael Lozano; Yuan Lu; Joelle Mak; Reza Malekzadeh; Leslie Mallinger; Wagner Marcenes; Lyn March; Robin Marks; Randall Martin; Paul McGale; John McGrath; Sumi Mehta; George A Mensah; Tony R Merriman; Renata Micha; Catherine Michaud; Vinod Mishra; Khayriyyah Mohd Hanafiah; Ali A Mokdad; Lidia Morawska; Dariush Mozaffarian; Tasha Murphy; Mohsen Naghavi; Bruce Neal; Paul K Nelson; Joan Miquel Nolla; Rosana Norman; Casey Olives; Saad B Omer; Jessica Orchard; Richard Osborne; Bart Ostro; Andrew Page; Kiran D Pandey; Charles D H Parry; Erin Passmore; Jayadeep Patra; Neil Pearce; Pamela M Pelizzari; Max Petzold; Michael R Phillips; Dan Pope; C Arden Pope; John Powles; Mayuree Rao; Homie Razavi; Eva A Rehfuess; Jürgen T Rehm; Beate Ritz; Frederick P Rivara; Thomas Roberts; Carolyn Robinson; Jose A Rodriguez-Portales; Isabelle Romieu; Robin Room; Lisa C Rosenfeld; Ananya Roy; Lesley Rushton; Joshua A Salomon; Uchechukwu Sampson; Lidia Sanchez-Riera; Ella Sanman; Amir Sapkota; Soraya Seedat; Peilin Shi; Kevin Shield; Rupak Shivakoti; Gitanjali M Singh; David A Sleet; Emma Smith; Kirk R Smith; Nicolas J C Stapelberg; Kyle Steenland; Heidi Stöckl; Lars Jacob Stovner; Kurt Straif; Lahn Straney; George D Thurston; Jimmy H Tran; Rita Van Dingenen; Aaron van Donkelaar; J Lennert Veerman; Lakshmi Vijayakumar; Robert Weintraub; Myrna M Weissman; Richard A White; Harvey Whiteford; Steven T Wiersma; James D Wilkinson; Hywel C Williams; Warwick Williams; Nicholas Wilson; Anthony D Woolf; Paul Yip; Jan M Zielinski; Alan D Lopez; Christopher J L Murray; Majid Ezzati; Mohammad A AlMazroa; Ziad A Memish
Journal:  Lancet       Date:  2012-12-15       Impact factor: 79.321

5.  National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5·4 million participants.

Authors:  Goodarz Danaei; Mariel M Finucane; John K Lin; Gitanjali M Singh; Christopher J Paciorek; Melanie J Cowan; Farshad Farzadfar; Gretchen A Stevens; Stephen S Lim; Leanne M Riley; Majid Ezzati
Journal:  Lancet       Date:  2011-02-03       Impact factor: 79.321

6.  A Needs Assessment of Sub-Sahara African National Hypertension Organizations for Hypertension Prevention and Control Programs.

Authors:  Tej K Khalsa; Norm R C Campbell; Kimbree A Redburn; Daniel Lemogoum; Mark L Niebylski
Journal:  J Clin Hypertens (Greenwich)       Date:  2015-07-25       Impact factor: 3.738

7.  High Blood Pressure in Sub-Saharan Africa: Why Prevention, Detection, and Control are Urgent and Important.

Authors:  Norm R C Campbell; Pascal Bovet; Aletta Elisabeth Schutte; Daniel Lemogoum; Armand Seraphin Nkwescheu
Journal:  J Clin Hypertens (Greenwich)       Date:  2015-06-13       Impact factor: 3.738

8.  The World Hypertension League challenges hypertension and cardiovascular organizations to develop strategic plans for the prevention and control of hypertension.

Authors:  Norm R C Campbell; Dan T Lackland; Liu Lisheng; Xin-Hua Zhang; Peter M Nilsson; Kimbree A Redburn; Mark L Niebylski
Journal:  J Clin Hypertens (Greenwich)       Date:  2015-04-10       Impact factor: 3.738

9.  A needs assessment of national hypertension organizations for hypertension prevention and control programs.

Authors:  Tej K Khalsa; Norm R C Campbell; Daniel T Lackland; Liu Lisheng; Mark L Niebylski; Xin-Hua Zhang
Journal:  J Clin Hypertens (Greenwich)       Date:  2014-11-10       Impact factor: 3.738

Review 10.  WHO's supported interventions on salt intake reduction in the sub-Saharan Africa region.

Authors:  Chandralall Sookram; Davison Munodawafa; Peter Malekele Phori; Benoit Varenne; Abdikamal Alisalad
Journal:  Cardiovasc Diagn Ther       Date:  2015-06
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Authors:  J T Hertz; F M Sakita; P Manavalan; B T Mmbaga; N M Thielman; C A Staton
Journal:  Public Health       Date:  2019-08-08       Impact factor: 2.427

2.  Acute myocardial infarction under-diagnosis and mortality in a Tanzanian emergency department: A prospective observational study.

Authors:  Julian T Hertz; Francis M Sakita; Godfrey L Kweka; Alexander T Limkakeng; Sophie W Galson; Jinny J Ye; Tumsifu G Tarimo; Gloria Temu; Nathan M Thielman; Janet P Bettger; John A Bartlett; Blandina T Mmbaga; Gerald S Bloomfield
Journal:  Am Heart J       Date:  2020-06-05       Impact factor: 4.749

3.  One-Year Outcomes and Factors Associated With Mortality Following Acute Myocardial Infarction in Northern Tanzania.

Authors:  Julian T Hertz; Francis M Sakita; Godfrey L Kweka; Tumsifu G Tarimo; Sumana Goli; Sainikitha Prattipati; Janet P Bettger; Nathan M Thielman; Gerald S Bloomfield
Journal:  Circ Cardiovasc Qual Outcomes       Date:  2022-03-18

4.  Diagnosis, Prevalence, Awareness, Treatment, Prevention, and Control of Hypertension in Cameroon: Protocol for a Systematic Review and Meta-Analysis of Clinic-Based and Community-Based Studies.

Authors:  Barthelemy Kuate Defo; Jean Claude Mbanya; Jean-Claude Tardif; Olugbemiga Ekundayo; Sylvie Perreault; Louise Potvin; Robert Cote; Andre Pascal Kengne; Simeon Pierre Choukem; Felix Assah; Samuel Kingue; Lucie Richard; Roland Pongou; Katherine Frohlich; Jude Saji; Pierre Fournier; Eugene Sobngwi; Valery Ridde; Marie-Pierre Dubé; Simon De Denus; Wilfred Mbacham; Jean-Philippe Lafrance; Dickson Shey Nsagha; Warner Mampuya; Anastase Dzudie; Lyne Cloutier; Christina Zarowsky; Agatha Tanya; Paul Ndom; Marie Hatem; Evelyne Rey; Louise Roy; Roxane Borgès Da Silva; Christian Dagenais; David Todem; Robert Weladji; Dora Mbanya; Elham Emami; Zakariaou Njoumemi; Laurence Monnais; Carl-Ardy Dubois
Journal:  JMIR Res Protoc       Date:  2017-05-29

5.  Knowledge of myocardial infarction symptoms and perceptions of self-risk in Tanzania.

Authors:  Julian T Hertz; Deng B Madut; Revogatus A Tesha; Gwamaka William; Ryan A Simmons; Sophie W Galson; Francis M Sakita; Venance P Maro; Gerald S Bloomfield; John A Crump; Matthew P Rubach
Journal:  Am Heart J       Date:  2019-01-15       Impact factor: 4.749

6.  Perceptions of chest pain and healthcare seeking behavior for chest pain in northern Tanzania: A community-based survey.

Authors:  Julian T Hertz; Deng B Madut; Revogatus A Tesha; Gwamaka William; Ryan A Simmons; Sophie W Galson; Francis M Sakita; Venance P Maro; Gerald S Bloomfield; John A Crump; Matthew P Rubach
Journal:  PLoS One       Date:  2019-02-12       Impact factor: 3.240

7.  Provider-perceived barriers to diagnosis and treatment of acute coronary syndrome in Tanzania: a qualitative study.

Authors:  Julian T Hertz; Godfrey L Kweka; Preeti Manavalan; Melissa H Watt; Francis M Sakita
Journal:  Int Health       Date:  2020-02-12       Impact factor: 2.473

8.  Hypertension and Obesity in Dakar, Senegal.

Authors:  Enguerran Macia; Lamine Gueye; Priscilla Duboz
Journal:  PLoS One       Date:  2016-09-13       Impact factor: 3.240

9.  Comparative effectiveness of antihypertensive drugs prescribed in Ethiopian healthcare practice: A pilot prospective, randomized, open label study.

Authors:  Hayelom Gebrekirstos Mengesha; Abraha Hailu Welegerima; Abera Hadgu; Haftom Temesgen; Mala George Otieno; Kiflom Tsegay; Tedros Fisseha; Samuel Getachew; Zekarias Merha; Helen Tewodros; Jiksa Dabessa; Berhane Gebreegzabher; Pammla Petrucka
Journal:  PLoS One       Date:  2018-09-11       Impact factor: 3.240

10.  A comparative study of hematological parameters between hypertensive and normotensive individuals in Harar, eastern Ethiopia.

Authors:  Beza Sileshi; Fekadu Urgessa; Moges Wordofa
Journal:  PLoS One       Date:  2021-12-07       Impact factor: 3.240

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