Literature DB >> 26405568

Tumor cell-derived microparticles: a new form of cancer vaccine.

Huafeng Zhang1, Bo Huang1.   

Abstract

For cancer vaccines, tumor antigen availability is currently not an issue due to technical advances. However, the generation of optimal immune stimulation during vaccination is challenging. We have recently demonstrated that tumor cell-derived microparticles (MP) can function as a new form of potent cancer vaccine by efficiently activating type I interferon pathway in a cGAS/STING dependent manner.

Entities:  

Keywords:  cGAS; cancer vaccine; dendritic cells; microparticle; type I IFN

Year:  2015        PMID： 26405568      PMCID： PMC4570097          DOI： 10.1080/2162402X.2015.1017704

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

Review 1.  Microparticles: protagonists of a novel communication network for intercellular information exchange.

Authors:  Sebastian F Mause; Christian Weber
Journal:  Circ Res       Date:  2010-10-29       Impact factor: 17.367

2.  Cell-free tumor microparticle vaccines stimulate dendritic cells via cGAS/STING signaling.

Authors:  Huafeng Zhang; Ke Tang; Yi Zhang; Ruihua Ma; Jingwei Ma; Yong Li; Shunqun Luo; Xiaoyu Liang; Tiantian Ji; Zhichao Gu; Jinzhi Lu; Wei He; Xuetao Cao; Yonghong Wan; Bo Huang
Journal:  Cancer Immunol Res       Date:  2014-12-04       Impact factor: 11.151

Review 3.  The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling.

Authors:  Xin Cai; Yu-Hsin Chiu; Zhijian J Chen
Journal:  Mol Cell       Date:  2014-04-24       Impact factor: 17.970

4.  Delivery of chemotherapeutic drugs in tumour cell-derived microparticles.

Authors:  Ke Tang; Yi Zhang; Huafeng Zhang; Pingwei Xu; Jing Liu; Jingwei Ma; Meng Lv; Dapeng Li; Foad Katirai; Guan-Xin Shen; Guimei Zhang; Zuo-Hua Feng; Duyun Ye; Bo Huang
Journal:  Nat Commun       Date:  2012       Impact factor: 14.919

Review 5.  Whole tumor antigen vaccines.

Authors:  Cheryl Lai-Lai Chiang; Fabian Benencia; George Coukos
Journal:  Semin Immunol       Date:  2010-03-30       Impact factor: 11.130

Review 6.  Role of type I interferon in inducing a protective immune response: perspectives for clinical applications.

Authors:  Paola Rizza; Franca Moretti; Imerio Capone; Filippo Belardelli
Journal:  Cytokine Growth Factor Rev       Date:  2014-10-30       Impact factor: 7.638

7.  Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors.

Authors:  Tiziana Di Pucchio; Lorenzo Pilla; Imerio Capone; Maria Ferrantini; Enrica Montefiore; Francesca Urbani; Roberto Patuzzo; Elisabetta Pennacchioli; Mario Santinami; Agata Cova; Gloria Sovena; Flavio Arienti; Claudia Lombardo; Arianna Lombardi; Patrizia Caporaso; Stefania D'Atri; Paolo Marchetti; Enzo Bonmassar; Giorgio Parmiani; Filippo Belardelli; Licia Rivoltini
Journal:  Cancer Res       Date:  2006-05-01       Impact factor: 12.701

8.  Microparticles released by Listeria monocytogenes-infected macrophages are required for dendritic cell-elicited protective immunity.

Authors:  Yi Zhang; Ruihua Zhang; Huafeng Zhang; Jing Liu; Zhuoshun Yang; Pingwei Xu; Wenqian Cai; Geming Lu; Miao Cui; Reto A Schwendener; Huang-Zhong Shi; Huabao Xiong; Bo Huang
Journal:  Cell Mol Immunol       Date:  2012-10-08       Impact factor: 11.530

Review 9.  The roles of tumor-derived exosomes in cancer pathogenesis.

Authors:  Chenjie Yang; Paul D Robbins
Journal:  Clin Dev Immunol       Date:  2011-11-30

Review 10.  Type I Interferons as Stimulators of DC-Mediated Cross-Priming: Impact on Anti-Tumor Response.

Authors:  Giovanna Schiavoni; Fabrizio Mattei; Lucia Gabriele
Journal:  Front Immunol       Date:  2013-12-25       Impact factor: 7.561
  10 in total
  8 in total

1.  Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.

Authors:  Wenqian Dong; Huafeng Zhang; Xiaonan Yin; Yuying Liu; Degao Chen; Xiaoyu Liang; Xun Jin; Jiadi Lv; Jingwei Ma; Ke Tang; Zhuowei Hu; Xiaofeng Qin; Bo Huang
Journal:  Oncoimmunology       Date:  2017-01-19       Impact factor: 8.110

2.  Particulate mediators of the bystander effect linked to suicide and interferon-β transgene expression in melanoma cells.

Authors:  Lucrecia Agnetti; Chiara Fondello; María Florencia Arbe; Gerardo C Glikin; Liliana M E Finocchiaro
Journal:  Gene Ther       Date:  2020-03-03       Impact factor: 5.250

Review 3.  Deciphering the role of ectosomes in cancer development and progression: focus on the proteome.

Authors:  Magdalena Surman; Ewa Stępień; Dorota Hoja-Łukowicz; Małgorzata Przybyło
Journal:  Clin Exp Metastasis       Date:  2017-03-19       Impact factor: 5.150

Review 4.  An Update on Novel Therapeutic Warfronts of Extracellular Vesicles (EVs) in Cancer Treatment: Where We Are Standing Right Now and Where to Go in the Future.

Authors:  Muhammad Babar Khawar; Muddasir Hassan Abbasi; Zerwa Siddique; Amin Arif; Nadeem Sheikh
Journal:  Oxid Med Cell Longev       Date:  2019-07-25       Impact factor: 6.543

Review 5.  cGAS-STING pathway in cancer biotherapy.

Authors:  Yang Wang; Jingwen Luo; Aqu Alu; Xuejiao Han; Yuquan Wei; Xiawei Wei
Journal:  Mol Cancer       Date:  2020-09-04       Impact factor: 27.401

Review 6.  The potential applications of microparticles in the diagnosis, treatment, and prognosis of lung cancer.

Authors:  Yu Liu; Sufei Wang; Hui Xia; Xueyun Tan; Siwei Song; Shujing Zhang; Daquan Meng; Qing Chen; Yang Jin
Journal:  J Transl Med       Date:  2022-09-05       Impact factor: 8.440

7.  Tumor-Derived Microvesicles Modulate Antigen Cross-Processing via Reactive Oxygen Species-Mediated Alkalinization of Phagosomal Compartment in Dendritic Cells.

Authors:  Federico Battisti; Chiara Napoletano; Hassan Rahimi Koshkaki; Francesca Belleudi; Ilaria Grazia Zizzari; Ilary Ruscito; Sara Palchetti; Filippo Bellati; Pierluigi Benedetti Panici; Maria Rosaria Torrisi; Giulio Caracciolo; Fabio Altieri; Marianna Nuti; Aurelia Rughetti
Journal:  Front Immunol       Date:  2017-09-25       Impact factor: 7.561

8.  Tumor-Derived Microvesicles Enhance Cross-Processing Ability of Clinical Grade Dendritic Cells.

Authors:  Marco Dionisi; Claudia De Archangelis; Federico Battisti; Hassan Rahimi Koshkaki; Francesca Belleudi; Ilaria Grazia Zizzari; Ilary Ruscito; Christian Albano; Alessandra Di Filippo; Maria Rosaria Torrisi; Pierluigi Benedetti Panici; Chiara Napoletano; Marianna Nuti; Aurelia Rughetti
Journal:  Front Immunol       Date:  2018-11-05       Impact factor: 7.561
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.