Literature DB >> 26405325

Inhaler Use in Hospitalized Patients with Chronic Obstructive Pulmonary Disease or Asthma: Assessment of Wasted Doses.

Sami Sakaan1, Dagny Ulrich2, Jenny Luo2, Christopher K Finch3, Timothy H Self4.   

Abstract

BACKGROUND: Hospitalized patients with chronic obstructive pulmonary disease (COPD) or asthma routinely have inhaled medications ordered for acute and maintenance therapy. Treatment may be administered via metered-dose inhaler (MDI) or dry-powder inhaler (DPI). These products must be appropriately labeled to be released home with the patient or discarded before discharge.
OBJECTIVE: To assess the amount and estimated cost of wasted doses of medications via MDI or DPI for hospitalized patients with COPD/asthma.
METHODS: A retrospective study was conducted at a university-affiliated hospital. Patients admitted between January 2011 and June 2012 with a primary diagnosis of COPD or COPD with asthma and who were ≥40 years of age were included. Information collected included use of albuterol, ipratropium, inhaled corticosteroids, long-acting beta agonist, or tiotropium and whether treatments were given by nebulizer, MDI, MDI plus valved holding chamber (VHC), or DPI. The number of doses dispensed, as well as doses not used, via MDI, MDI + VHC, or DPI were collected from electronic medical records. Costs associated with wasted medications were evaluated.
RESULTS: Of 555 patient admissions screened, 478 (mean age, 66 years; 58% women; 74% African American) met study criteria. Of the total MDI or DPI doses dispensed, 87% were wasted, and associated hospital cost was approximately $86,973.
CONCLUSIONS: Substantial waste of inhaled medications was found in our study. Practical strategies are needed to reduce wasted inhalers. Further assessment of this problem is needed in other US hospitals.

Entities:  

Keywords:  hospitalized COPD patients; inhalers; waste

Year:  2015        PMID: 26405325      PMCID: PMC4567205          DOI: 10.1310/hpj5005-386

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN: 0018-5787


  13 in total

1.  Substitution of metered-dose inhalers for hand-held nebulizers. Success and cost savings in a large, acute-care hospital.

Authors:  D L Bowton; W M Goldsmith; E F Haponik
Journal:  Chest       Date:  1992-02       Impact factor: 9.410

2.  A review and economic evaluation of bronchodilator delivery methods in hospitalized patients.

Authors:  M O Turner; A Gafni; D Swan; J M FitzGerald
Journal:  Arch Intern Med       Date:  1996-10-14

3.  Nebulizer vs spacer for bronchodilator delivery in patients hospitalized for acute exacerbations of COPD.

Authors:  R B Berry; R A Shinto; F H Wong; J A Despars; R W Light
Journal:  Chest       Date:  1989-12       Impact factor: 9.410

4.  Aerosol bronchodilator delivery methods. Relative impact on pulmonary function and cost of respiratory care.

Authors:  W Summer; R Elston; L Tharpe; S Nelson; E F Haponik
Journal:  Arch Intern Med       Date:  1989-03

5.  Automatic replacement of albuterol nebulizer therapy by metered-dose inhaler and valved holding chamber.

Authors:  Leslie Hendeles; Randy C Hatton; Timothy J Coons; Leah Carlson
Journal:  Am J Health Syst Pharm       Date:  2005-05-15       Impact factor: 2.637

6.  Cost-benefit comparison of aerosol bronchodilator delivery methods in hospitalized patients.

Authors:  A C Jasper; Z Mohsenifar; S Kahan; H S Goldberg; S K Koerner
Journal:  Chest       Date:  1987-04       Impact factor: 9.410

7.  A model for conversion from small volume nebulizer to metered dose inhaler aerosol therapy.

Authors:  M F Tenholder; M J Bryson; W L Whitlock
Journal:  Chest       Date:  1992-03       Impact factor: 9.410

8.  Effect of educational and policy interventions on institutional utilization of wet nebulization respiratory drugs and portable inhalers.

Authors:  Donna O Lowe; Heather Lummis; Ying Zhang; Ingrid S Sketris
Journal:  Can J Clin Pharmacol       Date:  2008-09-05

9.  Nebulisers or spacers for the administration of bronchodilators to those with asthma attending emergency departments?

Authors:  Naomi Mason; Nicola Roberts; Nick Yard; Martyn R Partridge
Journal:  Respir Med       Date:  2008-04-18       Impact factor: 3.415

Review 10.  Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.

Authors:  Klaus F Rabe; Suzanne Hurd; Antonio Anzueto; Peter J Barnes; Sonia A Buist; Peter Calverley; Yoshinosuke Fukuchi; Christine Jenkins; Roberto Rodriguez-Roisin; Chris van Weel; Jan Zielinski
Journal:  Am J Respir Crit Care Med       Date:  2007-05-16       Impact factor: 21.405

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  1 in total

1.  Evaluation of Bronchodilator Use During Chronic Obstructive Pulmonary Disease Exacerbation Inpatient Admissions.

Authors:  Sarah E Petite; Julie A Murphy
Journal:  Hosp Pharm       Date:  2018-04-10
  1 in total

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