| Literature DB >> 26404393 |
Gavan Holloway1, Rebecca I Johnson1, Yilin Kang2, Vi T Dang1, Diana Stojanovski2, Barbara S Coulson1.
Abstract
Specific roles have been ascribed to each of the 12 known rotavirus proteins apart from the non-structural protein 6 (NSP6). However, NSP6 may be present at sites of viral replication within the cytoplasm. Here we report that NSP6 from diverse species of rotavirus A localizes to mitochondria via conserved sequences in a predicted N-terminal a-helix. This suggests that NSP6 may affect mitochondrial functions during rotavirus infection.Entities:
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Year: 2015 PMID： 26404393 DOI： 10.1099/jgv.0.000294
Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891