Literature DB >> 26404175

Clinical and Neurophysiologic Characteristics of Unprovoked Seizures in Patients Diagnosed With Dementia.

Rani A Sarkis1, Bradford C Dickerson1, Andrew J Cole1, Zeina N Chemali1.   

Abstract

Seizures are a common comorbid condition in patients with dementia, but their characteristics have been poorly described. The authors performed a retrospective chart review using ICD-9 diagnosis codes consistent with seizures and with dementia. Seventy-seven patients were identified. Average age at onset was 68.1 years for cognitive symptoms, 71.5 years for dementia, and 73.9 years for seizures. Seizures preceded or followed cognitive symptoms (4.3 years before and 18.7 years after). At last follow-up, 12% of patients continued to have seizures. Findings show that unprovoked seizures can precede or follow the onset of dementia, but these seizures are controlled with medications in the majority of patients.

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Year:  2015        PMID: 26404175     DOI: 10.1176/appi.neuropsych.15060143

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN: 0895-0172            Impact factor:   2.198


  23 in total

Review 1.  Epileptic activity in Alzheimer's disease: causes and clinical relevance.

Authors:  Keith A Vossel; Maria C Tartaglia; Haakon B Nygaard; Adam Z Zeman; Bruce L Miller
Journal:  Lancet Neurol       Date:  2017-04       Impact factor: 44.182

2.  Relative Incidence of Seizures and Myoclonus in Alzheimer's Disease, Dementia with Lewy Bodies, and Frontotemporal Dementia.

Authors:  Alexander J Beagle; Sonja M Darwish; Kamalini G Ranasinghe; Alice L La; Elissaios Karageorgiou; Keith A Vossel
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

3.  Treatment of Seizures in Older Patients with Dementia.

Authors:  Benjamin Cretin
Journal:  Drugs Aging       Date:  2020-12-14       Impact factor: 3.923

4.  The neurophysiology and seizure outcomes of late onset unexplained epilepsy.

Authors:  Rani A Sarkis; Louis Beers; Emile Farah; Mohammad Al-Akaidi; Yuxiang Zhang; Joseph J Locascio; Michael J Properzi; Aaron P Schultz; Jasmeer P Chhatwal; Keith A Johnson; Reisa A Sperling; Page B Pennell; Gad A Marshall
Journal:  Clin Neurophysiol       Date:  2020-09-19       Impact factor: 3.708

5.  Association of Late-Onset Unprovoked Seizures of Unknown Etiology With the Risk of Developing Dementia in Older Veterans.

Authors:  Ophir Keret; Tina D Hoang; Feng Xia; Howard J Rosen; Kristine Yaffe
Journal:  JAMA Neurol       Date:  2020-06-01       Impact factor: 18.302

6.  Recurrent Epileptic Auras As a Presenting Symptom of Alzheimer's Disease.

Authors:  Rani A Sarkis; Kim C Willment; Seth A Gale; Barbara A Dworetzky
Journal:  Front Neurol       Date:  2017-07-24       Impact factor: 4.003

7.  Silent hippocampal seizures and spikes identified by foramen ovale electrodes in Alzheimer's disease.

Authors:  Alice D Lam; Gina Deck; Alica Goldman; Emad N Eskandar; Jeffrey Noebels; Andrew J Cole
Journal:  Nat Med       Date:  2017-05-01       Impact factor: 53.440

8.  Circadian and Brain State Modulation of Network Hyperexcitability in Alzheimer's Disease.

Authors:  Rosalind Brown; Alice D Lam; Alfredo Gonzalez-Sulser; Andrew Ying; Mary Jones; Robert Chang-Chih Chou; Makis Tzioras; Crispin Y Jordan; Izabela Jedrasiak-Cape; Anne-Laure Hemonnot; Maurice Abou Jaoude; Andrew J Cole; Sydney S Cash; Takashi Saito; Takaomi Saido; Richard R Ribchester; Kevan Hashemi; Iris Oren
Journal:  eNeuro       Date:  2018-05-17

9.  Association of epileptiform abnormalities and seizures in Alzheimer disease.

Authors:  Alice D Lam; Rani A Sarkis; Kyle R Pellerin; Jin Jing; Barbara A Dworetzky; Daniel B Hoch; Claire S Jacobs; Jong Woo Lee; Daniel S Weisholtz; Rodrigo Zepeda; M Brandon Westover; Andrew J Cole; Sydney S Cash
Journal:  Neurology       Date:  2020-08-06       Impact factor: 9.910

Review 10.  Amyloid-β: a potential link between epilepsy and cognitive decline.

Authors:  Michele Romoli; Arjune Sen; Lucilla Parnetti; Paolo Calabresi; Cinzia Costa
Journal:  Nat Rev Neurol       Date:  2021-06-11       Impact factor: 42.937

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