Literature DB >> 26403670

Study of the early management of acute pancreatitis.

Maryam Nesvaderani1, Guy D Eslick1, Shadi Faraj1, Daniel Vagg1, Michael R Cox1.   

Abstract

BACKGROUND: Acute pancreatitis (AP) is a common acute surgical presentation with evidence-based guidelines for early management. The aim of this study was to assess the compliance to the published guidelines in patients presenting with AP in Western Sydney.
METHODS: A retrospective case note audit was conducted for all patients with a confirmed diagnosis of AP from 2008 to 2011 in Western Sydney.
RESULTS: There were 932 patients. The mortality was low for mild (0.7%) and severe (1.2%) AP. There was an under-utilization of ultrasound (U/S) with 239 (25.6%) patients not having a U/S. There was an over-utilization of early (within 72 h) computed tomography scanning for diagnosis (31.1%), assessment of severity (16.1%) and assessment for the presence of complications (7.3%). Inappropriate prophylactic antibiotic usage occurred in 15.3% patients. Of 373 cases of gallstone pancreatitis, only 231 (69.1%) had a cholecystectomy within 4 weeks of presentation. There was an under-utilization of early endoscopic retrograde cholangiopancreatography for associated cholangitis (12.5%). Only 16 (18.8%) patients with severe pancreatitis received enteric feeding. In patients with pancreatic necrosis, 50% had invasive intervention delayed beyond 4 weeks and 69% had minimally invasive procedures performed prior to necrosectomy. Patients having a minimally invasive procedure initially showed an improvement in mortality compared with those who had primary necrosectomy (0 versus 40%, P = 0.025).
CONCLUSIONS: Although morbidity and mortality were acceptable, there was a failure to comply with evidence-based guidelines for the early management of pancreatitis. The results support for the development and auditing of protocols for the early assessment and treatment of AP in all hospitals.
© 2015 Royal Australasian College of Surgeons.

Entities:  

Keywords:  acute pancreatitis; antibiotic; early management; imaging

Mesh:

Year:  2015        PMID: 26403670     DOI: 10.1111/ans.13330

Source DB:  PubMed          Journal:  ANZ J Surg        ISSN: 1445-1433            Impact factor:   1.872


  3 in total

1.  Endoscopic Ultrasound for Routine Assessment in Idiopathic Acute Pancreatitis.

Authors:  Ryan Pereira; Guy Eslick; Michael Cox
Journal:  J Gastrointest Surg       Date:  2019-06-13       Impact factor: 3.452

2.  Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital.

Authors:  Vo Duy Thong; Trinh Thi Hong Anh; Bui Thi Huong Quynh; Ngo Thi Thanh Quyt
Journal:  JGH Open       Date:  2020-12-02

3.  Antibiotic-Induced Pathobiont Dissemination Accelerates Mortality in Severe Experimental Pancreatitis.

Authors:  Fernanda S Soares; Flávia C Amaral; Natália L C Silva; Matheus R Valente; Lorena K R Santos; Lívia H Yamashiro; Mara C Scheffer; Fernanda V E S Castanheira; Raphael G Ferreira; Laura Gehrke; José C Alves-Filho; Luciano P Silva; André Báfica; Fernando Spiller
Journal:  Front Immunol       Date:  2017-12-22       Impact factor: 7.561

  3 in total

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