Literature DB >> 264034

Pedicle fat grafts for the prevention of scar formation after laminectomy. An experimental study in dogs.

G G Gill, L Sakovich, E Thompson.   

Abstract

The formation of scar tissue always follows lumbar disc surgery and usually causes no difficulty. Reoperation may be necessary because of disc reherniation or because of the scar tissue itself. Reoperation is tedious and dangerous because of the presence of scar formation. Beginning in February 1975, the authors performed laminotomies in 107 dogs in an attempt to study the possibility of prevention of scar tissue formation about the dural sac and nerve roots. Gelfoam and Gelfilm were found to increase scar formation. Micropore tape and plastics such as polyethylene, mylar, and woven and smooth silastic were tried without complete success. Free fat grafts gave better protection than other substances, but it was found that pedicle grafts of fat gave more complete prevention of scar. The living pedicle fat grafts also prevented the usual closure of the laminotomy. The technique of pedicle fat grafts has also been used with success in 36 human patients to date.

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Year:  1979        PMID: 264034     DOI: 10.1097/00007632-197903000-00016

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  15 in total

1.  The effectiveness of poloxamer 407-based new anti-adhesive material in a laminectomy model in rats.

Authors:  Chang Hun Yu; Jae Hyup Lee; Hae-Ri Baek; Hwa Nam
Journal:  Eur Spine J       Date:  2011-12-10       Impact factor: 3.134

2.  Effect of amniotic membrane to reduce postlaminectomy epidural adhesion on a rat model.

Authors:  Hyu Jin Choi; Kyoung Beom Kim; Young-Min Kwon
Journal:  J Korean Neurosurg Soc       Date:  2011-06-30

3.  Role of a collagen membrane in adhesion prevention strategy for complex spinal surgeries.

Authors:  Jean-Charles LeHuec; Rachid Sadikki; Arnaud Cogniet; Julien Rigal; Hugues Demezon; Stéphane Aunoble
Journal:  Int Orthop       Date:  2015-04-14       Impact factor: 3.075

4.  Reduction of adhesion formation and promotion of wound healing after laminectomy by pharmacological inhibition of pro-inflammatory cytokines: an experimental study in the rat.

Authors:  Kjell Olmarker
Journal:  Eur Spine J       Date:  2010-07-10       Impact factor: 3.134

5.  Effect of fibrin glue on postlaminectomy scar formation.

Authors:  J Vaquero; A Arias; S Oya; R Martinez; M Zurita
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216

6.  Epidural scar tissue formation after spinal surgery: an experimental study.

Authors:  J Pospiech; F Pajonk; D Stolke
Journal:  Eur Spine J       Date:  1995       Impact factor: 3.134

7.  [The scar tissue protective effect of free autologous fatty tissue transplants. An animal experiment on spinal surgery].

Authors:  J Pospiech; R Kalff; F Pajonk; D Stolke; V Reinhardt
Journal:  Langenbecks Arch Chir       Date:  1994

8.  Effect of honey on peridural fibrosis formation after laminectomy in rats: a novel experimental study.

Authors:  Majid Reza Farrokhi; Mohammad Vasei; Saeed Fareghbal; Atefeh Bakhtazad
Journal:  Evid Based Complement Alternat Med       Date:  2011-01-23       Impact factor: 2.629

9.  Effects of low and high molecular weight hyaluronic acids on peridural fibrosis and inflammation in lumbar laminectomized rats.

Authors:  Jun Geol Lee; Sang Chul Lee; Yong Chul Kim; Young Jin Lim; Jae Hyuck Shin; Jae Hun Kim; Sang Hyun Park; Yun Ra Choi; Woo Seog Sim
Journal:  Korean J Pain       Date:  2011-11-30

10.  Evaluation of Perivascular Adhesion Formation in New Zealand White Rabbits Using Oxiplex and DuraSeal Xact Adhesion Barrier System.

Authors:  Fred Mo; James Yue; Jianghui Zhang; Kreg Howk; Allister Williams
Journal:  SAS J       Date:  2009-06-01
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