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Literature DB >> 26403165

Multitheragnostic Multi-GNRs Crystal-Seeded Magnetic Nanoseaurchin for Enhanced In Vivo Mesenchymal-Stem-Cell Homing, Multimodal Imaging, and Stroke Therapy.

Po-Jung Chen¹, Yi-Da Kang¹, Chen-Huan Lin², San-Yuan Chen¹, Chia-Hung Hsieh³, You-Yin Chen⁴, Chun-Wei Chiang², Wei Lee², Chung-Y Hsu⁵, Lun-De Liao^6,7, Chih-Tai Fan⁸, Meng-Lin Li^8,9, Woei-Cherng Shyu^2,10.

Abstract

A multifunctional nanoseaurchin probe in which mesoporous silica nanobeads with iron oxide nanoparticles embedded and multi-gold nanorods crystal-seeded are fabricated and labeled with umbilical cord mesenchymal stem cells through endocytosis. This nanoplatform enables efficient magnetic remote-controlled guiding for stem cell homing, and provides dual modalities of photoacoustic imaging and magnetic resonance imaging for in situ tracking and long-term monitoring to achieve therapeutic efficacy.

Entities: Chemical Disease

Keywords: magnetic resonance imaging; mesenchymal stem cells; multitheragnostic multi-GNRs crystal-seeded magnetic nanoseaurchin; photoacoustic imaging; stroke therapy

Mesh：

Substances：

Year: 2015 PMID： 26403165 DOI： 10.1002/adma.201502784

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

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Cited

17 in total

Review 1. Photoacoustic Molecular Imaging: From Multiscale Biomedical Applications Towards Early-Stage Theranostics.

Authors: Yajing Liu; Liming Nie; Xiaoyuan Chen
Journal: Trends Biotechnol Date: 2016-02-26 Impact factor: 19.536

2. Photoacoustic Imaging of Human Mesenchymal Stem Cells Labeled with Prussian Blue-Poly(l-lysine) Nanocomplexes.

Authors: Taeho Kim; Jeanne E Lemaster; Fang Chen; Jin Li; Jesse V Jokerst
Journal: ACS Nano Date: 2017-08-04 Impact factor: 15.881

3. Optimization of Multimodal Nanoparticles Internalization Process in Mesenchymal Stem Cells for Cell Therapy Studies.

Authors: Mariana P Nucci; Javier B Mamani; Fernando A Oliveira; Igor S Filgueiras; Arielly H Alves; Matheus H Theinel; Luiz D Rodrigues; Luciana Marti; Lionel F Gamarra
Journal: Pharmaceutics Date: 2022-06-12 Impact factor: 6.525

4. Stem cell homing, tracking and therapeutic efficiency evaluation for stroke treatment using nanoparticles: A systematic review.

Authors: Mariana Penteado Nucci; Igor Salerno Filgueiras; João Matias Ferreira; Fernando Anselmo de Oliveira; Leopoldo Penteado Nucci; Javier Bustamante Mamani; Gabriel Nery Albuquerque Rego; Lionel Fernel Gamarra
Journal: World J Stem Cells Date: 2020-05-26 Impact factor: 5.326

Review 5. Nanoarchitectured prototypes of mesoporous silica nanoparticles for innovative biomedical applications.

Authors: Ranjith Kumar Kankala; Ya-Hui Han; Hong-Ying Xia; Shi-Bin Wang; Ai-Zheng Chen
Journal: J Nanobiotechnology Date: 2022-03-12 Impact factor: 10.435

6. In vivo fate tracking of degradable nanoparticles for lung gene transfer using PET and Ĉerenkov imaging.

Authors: Kvar C L Black; Aida Ibricevic; Sean P Gunsten; Jeniree A Flores; Tiffany P Gustafson; Jeffery E Raymond; Sandani Samarajeewa; Ritu Shrestha; Simcha E Felder; Tianyi Cai; Yuefei Shen; Ann-Kathrin Löbs; Natalia Zhegalova; Deborah H Sultan; Mikhail Berezin; Karen L Wooley; Yongjian Liu; Steven L Brody
Journal: Biomaterials Date: 2016-05-03 Impact factor: 15.304

10. Dual-modal photoacoustic and magnetic resonance tracking of tendon stem cells with PLGA/iron oxide microparticles in vitro.

Authors: Man Lu; Xueqing Cheng; Jingzhen Jiang; TingTing Li; Zhenqi Zhang; Chialing Tsauo; Yin Liu; Zhigang Wang
Journal: PLoS One Date: 2018-04-02 Impact factor: 3.240