Literature DB >> 26401989

Size Changeable Nanocarriers with Nuclear Targeting for Effectively Overcoming Multidrug Resistance in Cancer Therapy.

Xing Guo1, Xiao Wei1, Yuting Jing2, Shaobing Zhou1,2.   

Abstract

A size changeable polymer micelle system with a dual shell, which increases in size under acidic pH conditions and is altered to smaller micelles, triggered by intracellular glutathione (GSH), is successfully developed. It is capable of direct delivering anticancer drugs to the nucleus of multidrug resistance (MDR) tumor cells for highly effective combating of drug resistant breast cancer.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cancer therapy; multidrug resistance; nanocarriers; nuclear targeting; reductive-sensitive materials

Mesh：

Substances：

Year:  2015        PMID： 26401989     DOI： 10.1002/adma.201502865

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  21 in total

1.  Dimeric Drug Polymeric Micelles with Acid-Active Tumor Targeting and FRET-Traceable Drug Release.

Authors:  Xing Guo; Lin Wang; Kayla Duval; Jing Fan; Shaobing Zhou; Zi Chen
Journal:  Adv Mater       Date:  2017-12-06       Impact factor: 30.849

Review 2.  Recent progress in nanomedicine for enhanced cancer chemotherapy.

Authors:  Guoqing Wei; Yu Wang; Guang Yang; Yi Wang; Rong Ju
Journal:  Theranostics       Date:  2021-04-19       Impact factor: 11.556

3.  Size and charge dual-transformable mesoporous nanoassemblies for enhanced drug delivery and tumor penetration.

Authors:  Liang Chen; Tiancong Zhao; Mengyao Zhao; Wenxing Wang; Caixia Sun; Lu Liu; Qin Li; Fan Zhang; Dongyuan Zhao; Xiaomin Li
Journal:  Chem Sci       Date:  2020-02-03       Impact factor: 9.825

Review 4.  Stimuli-Responsive Nanomedicines for Overcoming Cancer Multidrug Resistance.

Authors:  Lei Zhou; Hao Wang; Yaping Li
Journal:  Theranostics       Date:  2018-01-01       Impact factor: 11.556

5.  Polyanhydride micelles with diverse morphologies for shape-regulated cellular internalization and blood circulation.

Authors:  Guang Yang; Jie Wang; Dan Li; Shaobing Zhou
Journal:  Regen Biomater       Date:  2017-02-04

6.  Stepwise pH-responsive nanoparticles for enhanced cellular uptake and on-demand intracellular release of doxorubicin.

Authors:  Wei-Liang Chen; Fang Li; Yan Tang; Shu-di Yang; Ji-Zhao Li; Zhi-Qiang Yuan; Yang Liu; Xiao-Feng Zhou; Chun Liu; Xue-Nong Zhang
Journal:  Int J Nanomedicine       Date:  2017-06-06

7.  Sequentially Triggered Nanoparticles with Tumor Penetration and Intelligent Drug Release for Pancreatic Cancer Therapy.

Authors:  Xi He; Xinli Chen; Lisha Liu; Yu Zhang; Yifei Lu; Yujie Zhang; Qinjun Chen; Chunhui Ruan; Qin Guo; Chao Li; Tao Sun; Chen Jiang
Journal:  Adv Sci (Weinh)       Date:  2018-02-26       Impact factor: 16.806

8.  A simple reduction-sensitive micelles co-delivery of paclitaxel and dasatinib to overcome tumor multidrug resistance.

Authors:  Jun Li; Ruitong Xu; Xiao Lu; Jing He; Shidai Jin
Journal:  Int J Nanomedicine       Date:  2017-11-01

Review 9.  Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications.

Authors:  Wei Wu; Li Luo; Yi Wang; Qi Wu; Han-Bin Dai; Jian-Shu Li; Colm Durkan; Nan Wang; Gui-Xue Wang
Journal:  Theranostics       Date:  2018-04-30       Impact factor: 11.556

10.  Controlled synthesis and size effects of multifunctional mesoporous silica nanosystem for precise cancer therapy.

Authors:  Bin Ma; Lizhen He; Yuanyuan You; Jianbin Mo; Tianfeng Chen
Journal:  Drug Deliv       Date:  2018-11       Impact factor: 6.419
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